Abstract Hexim proteins are key RNA-dependent regulators of eukaryotic transcription through 7SK-dependent sequestration and inactivation of the kinase P-TEFb (Cdk9–CyclinT1/2)…
Abstract Supplementary Information: The online version contains supplementary material available at 10.1007/s00294-025-01327-8. Article type: Research Article Keywords: Cannabidiol, Microbiome, 16S…
Abstract Background: The prevalence of nonalcoholic steatohepatitis (NASH) is increasing every year, and there are very few approved therapeutic agents…
Abstract Insulin-like growth factor 2 mRNA-binding protein 2 (IMP2) is an RNA-binding protein that positively regulates m6A-modified RNAs involved in…
Abstract Activating signal co-integrator complex 1 (ASCC1) acts with ASCC-ALKBH3 complex in alkylation damage responses. ASCC1 uniquely combines two evolutionarily…
Abstract Dynein and kinesin motors mediate long-range intracellular transport, translocating towards microtubule minus and plus ends, respectively. Cargoes often undergo…
Abstract The RNA-binding motif protein RBM5 belongs to a family of multi-domain RNA binding proteins that regulate alternative splicing of…
Abstract Specificity of RNA-binding proteins for target sequences varies considerably. Yet, it is not understood how certain few proteins achieve…
Abstract The hemp flea beetle Psylliodes attenuata (Coleoptera: Chrysomelidae: Psylliodes) is a common pest of Cannabis sativa, including cultivars of…
Abstract A close epidemiological link has been reported between cannabis use and schizophrenia (SCZ). However, biochemical markers in living humans…