Metabolic Consequences of Gestational Cannabinoid Exposure
Abstract Up to 20% of pregnant women ages 18–24 consume cannabis during pregnancy. Moreover, clinical studies indicate that cannabis consumption…
δ9-tetrahydrocannabinol
A geospatiotemporal and causal inference epidemiological exploration of substance and cannabinoid exposure as drivers of rising US pediatric cancer rates
Abstract Background: Age-adjusted US total pediatric cancer incidence rates (TPCIR) rose 49% 1975–2015 for unknown reasons. Prenatal cannabis exposure has…
Assessment of Cannabidiol and Δ9-Tetrahydrocannabiol in Mouse Models of Medulloblastoma and Ependymoma
Abstract Simple Summary: Phytocannabinoids Δ9-tetrahydrocannabinol (THC) and cannabidiol (CBD) have been demonstrated to exhibit anti-cancer activity in preclinical models of…
The Role of Cannabinoids as Anticancer Agents in Pediatric Oncology
Abstract Simple Summary: The endocannabinoid system (ECS) is a complex signaling pathway system involved in the regulation of multiple functions…
Industrial, CBD, and Wild Hemp: How Different Are Their Essential Oil Profile and Antimicrobial Activity?
Abstract Hemp (Cannabis sativa L.) is currently one of the most controversial and promising crops. This study compared nine wild…
The Highs and Lows of Cannabis in Cancer Treatment and Bone Marrow Transplantation
Abstract In the last decade, we have observed an increased public and scientific interest in the clinical applications of medical…
New Perspectives on the Use of Cannabis in the Treatment of Psychiatric Disorders
Abstract Following the discovery of the endocannabinoid system and its potential as a therapeutic target for various pathological conditions, growing…
Microwave-Assisted Extraction of Cannabinoids in Hemp Nut Using Response Surface Methodology: Optimization and Comparative Study
Abstract Hemp nut is commonly incorporated into several food preparations; however, most countries set regulations for hemp products according to…
Effects of chronic Δ9-tetrahydrocannabinol treatment on Rho/Rho-kinase signalization pathway in mouse brain
Abstract Δ9-Tetrahydrocannabinol (Δ9-THC) shows its effects by activating cannabinoid receptors which are on some tissues and neurons. Cannabinoid systems have…
The Potential Role of Cannabinoids in Modulating Serotonergic Signaling by Their Influence on Tryptophan Metabolism
Abstract Phytocannabinoids present in Cannabis plants are well known to exert potent anti-inflammatory and immunomodulatory effects. Previously, we have demonstrated…