Therapeutic potential of cannabinoids for treating atopic dermatitis
Abstract This review aims to assess the therapeutic potential of cannabinoids as complementary treatments for atopic dermatitis. Atopic dermatitis (AD)…
Δ-9-tetrahydrocannabinol
Predicting Δ‑9-Tetrahydrocannabinol-Induced Psychoactive and Cognitive Effects: A PBPK–PD Approach to Quantifying Feeling High and Reduced Alertness
Abstract The increasing use of cannabis for medicinal and recreational purposes highlights the need to understand its psychoactive effects. Δ-9-tetrahydrocannabinol…
Cannabinoids in Treating Chemotherapy-Induced Nausea and Vomiting, Cancer-Associated Pain, and Tumor Growth
Abstract Cannabis has been used as an herbal remedy for thousands of years, and recent research indicates promising new uses…
Cannabis sativa demonstrates anti-hepatocellular carcinoma potentials in animal model: in silico and in vivo studies of the involvement of Akt
Abstract Background: Targeting protein kinase B (Akt) and its downstream signaling proteins are promising options in designing novel and potent…
The Protective Effect of CBD in a Model of In Vitro Ischemia May Be Mediated by Agonism on TRPV2 Channel and Microglia Activation
Abstract Cannabinoids, used for centuries for recreational and medical purposes, have potential therapeutic value in stroke treatment. Cannabidiol (CBD), a…
Cannabinoids for the treatment of cannabis use disorder: New avenues for reaching and helping youth?
Abstract Cannabis use peaks during adolescence and emerging adulthood, and cannabis use disorder (CUD) is associated with a wide range…
Efficacy of Cannabidiol for Δ-9-Tetrahydrocannabinol-Induced Psychotic Symptoms, Schizophrenia, and Cannabis Use Disorders: A Narrative Review
Abstract Although cannabis’ major psychoactive component, Δ-9-tetrahydrocannabinol (THC), has been linked to both earlier onset and poorer outcomes of psychotic…
Unraveling the Intoxicating and Therapeutic Effects of Cannabis Ingredients on Psychosis and Cognition
Abstract Research evidence suggests a dose–response relationship for the association between cannabis use and risk of psychosis. Such relationship seems…
Bioavailability study of dronabinol oral solution versus dronabinol capsules in healthy volunteers
Abstract Background: Dronabinol, a pharmaceutical Δ-9-tetrahydrocannabinol, was originally developed as an oral capsule. This study evaluated the bioavailability of a…