The Prevalence of Potential Drug-Drug-Gene Interactions: A Descriptive Study Using Swiss Claims Data
Abstract Purpose: We aimed to determine the prevalence of interactions between PGx drugs metabolized by CYP2C9, CYP2C19, and CYP2D6 and…
Science Article
SRCIN1 promotes thyroid carcinoma growth by activating Wnt signaling pathway
Abstract Supplementary Information: The online version contains supplementary material available at 10.1038/s41598-025-16674-2. Article type: Research Article Keywords: SRCIN1, Thyroid cancer,…
Exploring the multifaceted roles of glutamate oxaloacetate transaminase 1 as a biomarker and therapeutic target in colorectal cancer and pan-cancer analyses
Abstract Supplementary Information: The online version contains supplementary material available at 10.1007/s12672-025-03461-8. Article type: Research Article Keywords: Colorectal cancer, Glutamate…
Microglial activation is inhibited by selective anti-seizure medications
Abstract Objective: To investigate the anti-inflammatory properties of anti-seizure medications (ASMs) administered to patients with drug-resistant epilepsy (DRE) and the…
Influence of Raw‐Material Processing on Gold and Silver Nanoparticles Stability Using Ultrasound‐Extracted Pink‐Pepper Compounds
Abstract The ultrasound‐assisted green synthesis of gold (AuNPs) and silver nanoparticles (AgNPs) from Schinus terebinthifolius extracts delivered stable colloids whose…
A review on multi-omics integration for aiding study design of large scale TCGA cancer datasets
Abstract Background: Rapid advancements in high-throughput sequencing technologies allow for detailed and accurate measurement of omics features within their biological…
Effects of Inhaled Tobacco and Cannabis Co-Use on Respiratory Health and Tobacco Cessation: An Official American Thoracic Society Research Statement
Abstract Background: Tobacco and cannabis are among the most widely used substances globally, and rates of co-use are on the…
Cannabinoid 1 receptor availability in posttraumatic stress disorder: A positron emission tomography study
Abstract The endocannabinoid system (ECS) plays a critical role in fear learning and maintenance and may, therefore, be implicated in…
Genome-Wide Identification of the TIFY Family in Cannabis sativa L. and Its Potential Functional Analysis in Response to Alkaline Stress and in Cannabinoid Metabolism
Abstract TIFY transcription factors play crucial regulatory roles in secondary metabolism and stress response. However, the expression patterns of the…
Quantitation of Cannabidiol (CBD) in brain regions and plasma following intranasal administration of a CBD nanoformulation
Abstract Background and objective: Delivering therapeutic drugs to the brain for neurological disorders remains challenging due to the restrictive nature…