Modulating Growth Factor Receptor Signaling to Promote Corneal Epithelial Homeostasis
Abstract The corneal epithelium is the first anatomical barrier between the environment and the cornea; it is critical for proper…
Science Article
Evaluating signaling bias for synthetic cannabinoid receptor agonists at the cannabinoid CB2 receptor
Abstract The rapid structural evolution and emergence of novel synthetic cannabinoid receptor agonists (SCRAs) in the recreational market remains a…
Characterization of cannabinoid plasma concentration, maternal health, and cytokine levels in a rat model of prenatal Cannabis smoke exposure
Abstract Cannabis sativa has gained popularity as a “natural substance”, leading many to falsely assume that it is not harmful.…
Cannabis and pathologies in dogs and cats: first survey of phytocannabinoid use in veterinary medicine in Argentina
Abstract Background: In animals, the endocannabinoid system regulates multiple physiological functions. Like humans, animals respond to preparations containing phytocannabinoids for…
AM1172 (a hydrolysis-resistant endocannabinoid analog that inhibits anandamide cellular uptake) reduces the viability of the various melanoma cells, but it exerts significant cytotoxic effects on healthy cells: an in vitro study based on isobolographic analysis
Abstract Background: Despite great advances in our understanding of the impact of cannabinoids on human organism, many of their properties…
Hemp Seed Cake Flour as a Source of Proteins, Minerals and Polyphenols and Its Impact on the Nutritional, Sensorial and Technological Quality of Bread
Abstract Hemp (Cannabis sativa L.) seeds contain a high concentration of proteins and biologically active compounds. The protein content is…
Pharmacokinetics of cannabidiol-/cannabidiolic acid-rich hemp oil in juvenile cynomolgus macaques (Macaca fascicularis)
Abstract Introduction: Cannabinoids are increasingly popular in human and veterinary medicine and have been studied as an alternative treatment for…
Extraction of Active Compounds from Mixtures of Hemp (Cannabis sativa) with Plants of the Zingiberaceae Family
Abstract Hemp is probably one of the most studied plants for its health-promoting properties, with countless documented and patented extraction…
Therapeutic use of medical Cannabis in neurological diseases: a clinical update
Abstract The use of medical Cannabis has increased in recent years due to changing legal circumstances in many countries. Approval…
Targeting Nrf2 Signaling Pathway in Cancer Prevention and Treatment: The Role of Cannabis Compounds
Abstract The development and progression of cancer are associated with the dysregulation of multiple pathways involved in cell proliferation and…