Presynaptic nanoscale components of retrograde synaptic signaling
Abstract While our understanding of the nanoscale architecture of anterograde synaptic transmission is rapidly expanding, the qualitative and quantitative molecular…
Science Article
Biobased Composites from Eugenol- and Coumarin-Derived Methacrylic Latex and Hemp Nanocellulose: Cross-Linking via [2 + 2] Photocycloaddition and Barrier Properties
Abstract A novel-biobased latex was synthesized by redox-initiated emulsion copolymerization of ethoxy dihydroeugenyl methacrylate with 5 wt % of a…
Exploring Cannabinoids as Potential Inhibitors of SARS-CoV-2 Papain-like Protease: Insights from Computational Analysis and Molecular Dynamics Simulations
Abstract The emergence of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has triggered a global COVID-19 pandemic, challenging healthcare…
Re-evaluation of the cardioprotective effects of cannabinoids against ischemia-reperfusion injury according to the IMproving Preclinical Assessment of Cardioprotective Therapies (IMPACT) criteria
Abstract Ischemic heart disease, associated with high morbidity and mortality, represents a major challenge for the development of drug-based strategies…
Mild Disease Course of Experimental Autoimmune Encephalomyelitis without Pertussis Toxin: Brain Transcriptome Analysis Reveals Similar Signaling to Active Lesions in Multiple Sclerosis
Abstract Experimental autoimmune encephalomyelitis (EAE) is a powerful model to study multiple sclerosis (MS). One of the approaches for EAE…
Comparative restriction enzyme analysis of methylation (CREAM) reveals methylome variability within a clonal in vitro cannabis population
Abstract The primary focus of medicinal cannabis research is to ensure the stability of cannabis lines for consistent administration of…
Physiological profiling of cannabidiol reveals profound inhibition of sensory neurons
Abstract The authors use high-content calcium imaging and patch clamp recordings to demonstrate broad inhibition by cannabidiol of multiple receptors,…
Trends of emergency department visits for cannabinoid hyperemesis syndrome in Nevada: An interrupted time series analysis
Abstract Cannabis-related emergency department visits have increased after legalization of cannabis for medical and recreational use. Accordingly, the incidence of…
Tandem Mass Tag-10plex (TMT-10plex) phosphoproteomics dataset for comprehensive analysis of active compounds with tyrosine kinase inhibition activity
Abstract Bioactive compounds derived from natural products demonstrate a wide range of beneficial properties in cancer treatment. One popular approach…
Revolutionizing Phenolic Content Determination in Vegetable Oils: A Cutting-Edge Approach Using Smartphone-Based Image Analysis
Abstract This study addressed the need for a more accessible and efficient method of analyzing phenolic content in vegetable oils.…