Assessing patient perceptions of off-label cannabidiol use for insomnia through sentiment analysis
Abstract Background: Recent global policy shifts have greatly expanded access to and the market for medicinal cannabis, broadening its availability…
Science Article
Exploring ASPN as a pan-cancer biomarker with a focus on gastric cancer
Abstract Background: Cancer remains a leading cause of mortality worldwide, posing a serious threat to public health. The ASPN protein…
Data-driven universal insights into tumorigenesis via hallmark networks
Abstract Cancers are complex diseases characterized by dynamic perturbations of regulatory networks across multiple hierarchical levels, which cannot be fully…
DOCK2 modulates immune checkpoint inhibitor responsiveness and prognosis in cutaneous melanoma through multi-omics and single-cell T cell dynamics profiling
Abstract Background: Skin cutaneous melanoma (SKCM) is a highly aggressive malignancy that arises from melanocytes and has been associated with…
Integrated Pan-Cancer Analysis and Experimental Verification of the Roles of Retinoid-Binding Proteins in Breast Cancer
Abstract Many cancers disrupt how vitamin A-related proteins control cell growth and death. We studied these proteins, especially RBP4 and…
Cannabis use and suicide: a case-control study based on integrative data analysis
Abstract Background: Cannabis use has been identified as a risk factor for depression, suicidal ideation, and suicide attempts. However, the…
Anti-Müllerian hormone plays a bidirectional role in cancer: a multi-database and multi-method study
Abstract Introduction: Anti-Müllerian hormone (AMH) has been variably associated with cancer risk. This study integrated a meta-analysis, Mendelian randomization (MR),…
EIF3M as a pan-cancer biomarker: prognostic significance and immune infiltration association
Abstract Background: EIF3M, a core subunit of eukaryotic translation initiation factor 3, plays a pivotal role in protein synthesis by…
A pan-cancer analysis of the oncogenic role of KDELR2 in human cancers
Abstract Background: KDELR2, a retrograde transport receptor involved in ER protein homeostasis, has emerged as a potential contributor to cancer…
Crop steering through osmotic stress can reduce height but reduced yield in medical Cannabis
Abstract Background: Precision water stress, achieved via osmotic stress, has the potential to control plant size and improve crop quality…