A Novel Glucosamine-Based Cannabidiol Complex Based on Intermolecular Bonding with Improved Water Solubility
Abstract In this study, a new, patented form of a water-soluble cannabidiol (CBD) complex was synthesised and tested. The formation…
Science Article
Dynamic changes of synergy relationship between lncRNA and immune checkpoint in cancer progression
Abstract In the battle between tumors and the immune system, immune evasion based on immune checkpoints (ICPs) is a critical…
Interpretable graph Kolmogorov–Arnold networks for multi-cancer classification and biomarker identification using multi-omics data
Abstract The integration of heterogeneous multi-omics datasets at a systems level remains a central challenge for developing analytical and computational…
Media Reports and Knowledge of e-Cigarette or Vaping Use-Associated Lung Injury Among Adolescents in California: Population-Based Cross-Sectional Study
Abstract Background: e-Cigarette or vaping use-associated lung injury (EVALI), first reported in July 2019, caused over 2807 hospitalizations and 68…
Substance use and mental health factors associated with self-reported higher risk cannabis use among people with HIV screened in primary care
Abstract Background: While cannabis use is prevalent among people with HIV (PWH), factors associated with higher-risk use require further study.…
The Safety and Effectiveness of Multi-Segment Cortical Bone Trajectory Screws in Adult Degenerative Scoliosis with Stenosis Among the Elderly: Minimum 5-year Follow-up Study
Abstract Purpose: To evaluate the long-term efficacy and safety of multi-segment cortical bone trajectory screws for treating mild adult degenerative…
Management and outcomes of patients with obstructive jaundice from pancreatobiliary diseases in Rwanda
Abstract Background: Obstructive jaundice from pancreatobiliary diseases represents a significant global health challenge, particularly in resource-limited settings like Rwanda. While…
1H, 13C, 15N backbone chemical shift assignment of P18ink4c from Danio rerio (zebrafish) using solution-state NMR spectroscopy
Abstract The INK4 family of proteins restricts uncontrolled cell cycle progression by inhibiting cyclin-dependent kinases 4 and 6. The family…
Systematic pan-cancer analysis identified NCOA4 as an immunological and prognostic biomarker and validated in lung adenocarcinoma
Abstract Background: Cancer immunotherapy has revolutionized treatment, yet predicting patient responses remains challenging. The potential of nuclear receptor coactivator 4…
Single‐Cell RNA Sequencing Reveals the Heterogeneity in Differentiation Trajectory and Tumor Microenvironment Leading to More Aggressive Phenotypes of Papillary Thyroid Cancer in Children and Young Adult Patients
Abstract The tumor ecosystem heterogeneity of papillary thyroid carcinoma (PTC) is poorly characterized in children and young adult patients (CAYA‐PTC).…