Rural inpatient hospitals and substance use—a 10-year retrospective analysis
Abstract Aim: To determine the burden and nature of substance use presentations within a defined rural region and provide an…
Science Article
Molecular targets of cannabinoids and their derivatives in epilepsy – a review with focus on CBD
Abstract In recent years, cannabinoids and their derivatives have been tested for efficacy in epilepsy therapy and related disorders. Many…
Long-Term Efficacy and Safety of Inhaled Cannabis Therapy for Painful Diabetic Neuropathy: A 5-Year Longitudinal Observational Study
Abstract Background/Objectives: Diabetic neuropathy (DN) is a prevalent complication of diabetes mellitus, affecting up to 50% of long-term patients and…
THC reverses SIV-induced senescence in astrocytes: possible compensatory mechanism against HIV associated brain injury?
Abstract Introduction: Despite effective combination antiretroviral therapy (cART), chronic neuroinflammation and glial dysfunction continues to be an important yet understudied…
The Endocannabinoid System in the Development and Treatment of Obesity: Searching for New Ideas
Abstract Obesity is a complex, multifactorial disease and a growing global health challenge associated with type 2 diabetes, cardiovascular disorders,…
The CB1 receptor: linking impulsivity and substance use disorder
Abstract The cannabinoid receptor type 1 (CB1R) is the most widely expressed G protein-coupled receptor in the brain, with high…
Waldo: Automated discovery of adverse events from unstructured self reports
Abstract Adverse event (AE) detection is labor-intensive and costly given the task is to find rare events. Automated solutions to…
Preclinical assessment of pharmacokinetics and anticonvulsant activity of CBDTech, a novel orally administered cannabidiol (CBD) formulation for seizure and epilepsy
Abstract Oral cannabidiol (CBD) product use is increasing despite suboptimal pharmacokinetics (PK) of currently available formulations. This study aimed to…
Investigating Links Between Prenatal Cannabis Exposure and Brain Development Using Magnetic Resonance Imaging Techniques: A Narrative Review
Abstract Understanding the impact of prenatal cannabis exposure (PCE) on brain development is increasingly important given rising cannabis use during…
A case report of schizoaffective bipolar disorder and the impact of medication adherence on creativity
Abstract Background: Artistic creativity is often observed in individuals with schizoaffective disorder, bipolar type, while medication adherence can be compromised…