Psychosocial Impacts of Non-Fatal Firearm Injuries on Youth: Findings from a Qualitative Study
Abstract Most adolescents and young adult victims of firearm violence survive, yet the mental and behavioral health outcomes associated with…
Science Article
Three-day delta-9-tetrahydrocannabinol (THC) exposure eliminates long-term depression in ventral tegmental area of young, but not adult mice
Abstract Ventral tegmental area (VTA) dopamine signaling plays a key role in reward learning and drug dependence. VTA dopamine cell…
Moving Away from One-Size-Fits-All: Assessing the Use of Pharmacogenetic-Guided Medication Therapy in Pediatric Patients with Chronic Pain
Abstract Background/Objectives: Pharmacogenetic (PGx) testing can predict drug efficacy, toxicity, and risk of adverse drug reactions (ADRs). However, PGx-guided prescribing…
Deciphering the role of Hashimoto’s Thyroiditis-related key genes in thyroid cancer via detailed in silico analysis followed by the experimental validation
Abstract Background: Thyroid cancer, characterized by significant genetic and epigenetic alterations, remains a critical focus of molecular oncology. This study…
Modulatory effect of metformin and its transporters on immune infiltration in tumor microenvironment: a bioinformatic study with experimental validation
Abstract Supplementary Information: The online version contains supplementary material available at 10.1007/s12672-025-02766-y. Article type: Research Article Keywords: Metformin, Organic cationic…
Cannabinoid Receptor Type 1 Availability in Individuals with a History of Childhood Trauma: A Positron Emission Tomography Study
Abstract Early life adversity has a lasting impact on the endocannabinoid (eCB) system based on animal models. However, the impact…
The effect of work-family conflict on staff nurses’ job performance: the mediating role of emotional intelligence
Abstract Background: Nurses often experience high levels of Work-Family Conflict (WFC) due to the demanding nature of their profession, which…
Lung microbiota: a new hope for treating acute respiratory distress syndrome?
Abstract The lung microbiota, present in healthy individuals, undergoes alterations in different diseases and is closely linked to changes in…
Whey Protein Isolate Hydrogels Containing Cannabidiol Support the Proliferation of Pre-Osteoblasts
Abstract Bone-associated pathologies are major contributors to chronic pathology statistics. Current gold standard treatments present limitations such as the ability…
Beyond Transposons: TIGD1 as a Pan-Cancer Biomarker and Immune Modulator
Abstract Background/Objectives: TIGD1 (Trigger Transposable Element Derived 1) is a recently identified oncogene with largely unexplored biological functions. Emerging evidence…