Early life outcomes of prenatal exposure to alcohol and synthetic cannabinoids in mice
Abstract Purpose: This study investigated the effects of prenatal co-exposure to alcohol and synthetic cannabinoids on offspring viability, physical development,…
Science Article
Revisiting the Gateway Drug Hypothesis for Cannabis: A Secondary Analysis of a Nationwide Survey Among Community Users in Japan
Abstract Aim: Cannabis has historically been used for medicinal and industrial purposes, but is strictly regulated worldwide due to the…
Understanding medical cannabis use internationally: Why definitions and context matter
Abstract Aims: To identify variation in identification of medical consumers using alternative self‐reported measures and assess whether differences in these…
Differential effects of S-allyl cysteine and cannabidiol on enterocytic and plasma amyloid-β in db/db diabetic mice
Abstract Peripheral amyloid-beta (Aβ), including those in bloodstream and intestine, is implicated in the pathogenesis of Alzheimer’s disease (AD). Additionally,…
Mother transformer: A High-Throughput, Cost-Effective in Planta Hairy Root Transformation Method for Cannabis
Abstract Background: Hairy root (HR) transformation assays mediated by Agrobacterium rhizogenes, both in vitro and ex vitro, are essential tools…
Accuracy of labeled THC potency across flower and concentrate cannabis products
Abstract High total tetrahydrocannabinol (THC) cannabis products are quickly gaining market share across the U.S., but it is unknown whether…
Exploring the interconnected properties of cannabidiol suspensions and orodispersible films
Abstract Supplementary Information: The online version contains supplementary material available at 10.1038/s41598-025-02859-2. Article type: Research Article Keywords: Colloidal dispersions, Polymeric…
Genetic diversity, population structure, and cannabinoid variation in feral Cannabis sativa germplasm from the United States
Abstract Supplementary Information: The online version contains supplementary material available at 10.1038/s41598-025-07912-8. Article type: Research Article Keywords: Cannabinoids, Genetic diversity,…
Inflammatory state moderates response to cannabis on negative affect and sleep quality in individuals with anxiety
Abstract Introduction: Inflammation has been implicated as an underlying pathology in negative affect and sleep disruption. Cannabinoids like delta-9-tetrahydrocannabinol (THC)…
The disordered p53 transactivation domain is the target of FOXO4 and the senolytic compound FOXO4-DRI
Abstract A central process contributing to the phenotype of aging is cellular senescence. We recently identified the FOXO4 – p53…