A Phase I Trial of the Pharmacokinetic Interaction Between Cannabidiol and Tacrolimus
Abstract One in six Americans uses cannabidiol‐based or cannabis‐derived products. Cannabidiol is a substrate of CYP3A, but its role as…
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Constructing methylation-driven ceRNA networks unveil tumor heterogeneity and predict patient prognosis
Abstract Cancer development involves a complex interplay between genetic and epigenetic factors, with emerging evidence highlighting the pivotal role of…
Engineering Nicotiana benthamiana for production of active cannabinoid synthases via secretory pathway optimization
Abstract The heterologous expression of CBDAS and THCAS in the secretory pathway of Nicotiana benthamiana leaves is influenced for a…
Prevalence of suicidal ideation and associated factors among pregnant women attending ANC follow-up clinic in Gondar Comprehensive Specialized Hospital, Northwest Ethiopia, 2022
Abstract Suicide is a worldwide concern and ranks as the third leading cause of death among individuals of reproductive age.…
Prevalence of treatment-resistant depression and associated factors among major depressive disorder follow-up patients at Saint Amanuel Mental Specialised Hospital in Ethiopia: a cross-sectional study
Abstract Abstract: Objectives: This study aimed to assess the prevalence of treatment-resistant depression (TRD) and associated factors among patients with…
Near-infrared diffuse optical characterization of human thyroid using ultrasound-guided hybrid time-domain and diffuse correlation spectroscopies
Abstract Thyroid vascularization and hemodynamics become altered in thyroid pathologies and could thus inform diagnostics, therapy planning, and follow-up. However,…
Prognostic Value and Immunological Role of POP7 in Clear Cell Renal Cell Carcinoma
Abstract Background: Studies have found that RNA-binding proteins (RBPs) are participated in the occurrence or development of tumours. However, the…
A randomized dose finding study of combination dronabinol and acetazolamide for the treatment of obstructive sleep apnea
Abstract Study Objectives: Current treatments for obstructive sleep apnea (OSA) are ineffective or not tolerated in a proportion of patients.…
Droperidol Plus Diphenhydramine for Symptom Improvement in Suspected Cannabinoid Hyperemesis Syndrome: A Prospective Cohort Study
Abstract Background: Cannabinoid Hyperemesis Syndrome (CHS) is characterized by recurrent, paroxysmal episodes of nausea, vomiting, and abdominal discomfort in chronic…
Leaf pigmentation in Cannabis sativa : Characterization of anthocyanin biosynthesis in colorful Cannabis varieties
Abstract Cannabis plants produce a spectrum of secondary metabolites, encompassing cannabinoids and more than 300 non‐cannabinoid compounds. Among these, anthocyanins…