Opioid Use Following Primary Unilateral Total Knee Arthroplasty Varies With Age
Abstract Background: Reducing unused prescribed opioids following arthroplasty procedures remains a challenge. The relationship between opioid consumption and age has…
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Changes in prenatal cannabis use and perceptions during the COVID-19 pandemic
Abstract Purpose: To understand the observed increase in prenatal cannabis use during the COVID-19 pandemic, this study compared differences in…
Tumor suppressing function of SLC16A7 in bladder cancer and its pan-cancer analysis
Abstract Background: Bladder cancer (BCa), a prevalent malignancy of the urinary tract, is associated with high recurrence and mortality rates.…
Cannabidiol as an immune modulator: A comprehensive review
Abstract Cannabidiol (CBD), a non-psychoactive phytocannabinoid derived from Cannabis sativa, has emerged as a promising therapeutic agent due to its…
RAP1GAP is a prognostic biomarker and correlates with immune infiltrates in bladder cancer
Abstract Background: The role of RAP1GAP in tumor progression has garnered increasing attention; however, its prognostic value and immunological influence…
Rapid quantification of whole seed fatty acid amount, composition, and shape phenotypes from diverse oilseed species with large differences in seed size
Abstract Background: Seed oils are widely used in the food, biofuel, and industrial feedstock industries, with their utility and value…
Planning, implementation, evaluation, and sustainment of digital health interventions for adolescent substance use prevention: a systematic review of influencing factors based on the RE-AIM framework
Abstract School-based health interventions can help prevent adolescent substance use, but their success depends on various factors affecting planning and…
Multi-ancestry genetic architecture of sleep duration and its relationship to other sleep and psychiatric phenotypes
Abstract Differences in sleep duration, quality, and timing are associated with variation in cognition, health outcomes, and quality of life.…
How THC works: Explaining ligand affinity for, and partial agonism of, cannabinoid receptor 1
Abstract Interaction with cannabinoid receptor 1 (CB1) partially determines the bioactivity of the phytocannabinoids. Consequently, there has also been significant…
Transcriptomic analysis of CDL-gated photoperiodic flowering mechanisms in cannabis and their responsiveness to R: FR ratios in controlled environment agriculture
Abstract While discrete regulatory mechanisms have been identified, a unified model for the transcriptional activation of photoperiodic flowering in short-day…