Dynamic regulation of the endocannabinoid system: implications for analgesia
Abstract The analgesic effects of cannabinoids are well documented, but these are often limited by psychoactive side-effects. Recent studies indicate…
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Hashish Body Packing: A Case Report
Abstract A 42-year-old African male was brought by the police to the emergency department under suspicion of drug smuggling by…
Testing Developmental Pathways to Antisocial Personality Problems
Abstract This study examined the development of antisocial personality problems (APP) in young adulthood from disruptive behaviors and internalizing problems…
High HIV Prevalence Among Men Who have Sex with Men in Soweto, South Africa: Results from the Soweto Men’s Study
Abstract The Soweto Men’s Study assessed HIV prevalence and associated risk factors among MSM in Soweto, South Africa. Using respondent…
Homeless in Dhaka: Violence, Sexual Harassment, and Drug-abuse
Abstract Bangladesh has experienced one of the highest urban population growth rates (around 7% per year) over the past three…
CB2 Cannabinoid Receptors Contribute to Bacterial Invasion and Mortality in Polymicrobial Sepsis
Abstract Background: Sepsis is a major healthcare problem and current estimates suggest that the incidence of sepsis is approximately 750,000…
Identification of candidate genes affecting Δ9-tetrahydrocannabinol biosynthesis in Cannabis sativa
Abstract RNA isolated from the glands of a Δ9-tetrahydrocannabinolic acid (THCA)-producing strain of Cannabis sativa was used to generate a…
From drugs to deprivation: a Bayesian framework for understanding models of psychosis
Abstract Introduction: Various experimental manipulations, usually involving drug administration, have been used to produce symptoms of psychosis in healthy volunteers.…
Standardized natural product cannabis in pain management and observations at a Canadian compassion society: a case report
Abstract An adult Caucasian male with excruciating pains following multiple traumas was monitored, daily, over one year while managing chronic…
Time-Dependent Vascular Effects of Endocannabinoids Mediated by Peroxisome Proliferator-Activated Receptor Gamma (PPARγ)
Abstract The aim of the present study was to examine whether endocannabinoids cause PPARγ-mediated vascular actions. Functional vascular studies were…