Altered Mesolimbic Dopamine System in THC Dependence
Abstract To explore the functional consequences of cannabinoid withdrawal in the rat mesolimbic dopamine system, we investigated the anatomical morphology…
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Cannabinoid system and cyclooxygenases inhibitors
Abstract Rationale. The cannabinoid system consists of a complex array of receptors, substances with agonist/antagonist properties for those receptors, biosynthetic…
Durability of Starch Based Biodegradable Plastics Reinforced with Manila Hemp Fibers
Abstract The biodegradability of Manila hemp fiber reinforced biodegradable plastics was studied for 240 days in a natural soil and…
Cannabinoid Receptor 2 Deficiency in Haematopoietic cells Aggravates Early Atherosclerosis in LDL Receptor Deficient Mice
Abstract Objective: The cannabinoid receptor 2 (CB2) has been implicated to play a role in various inflammatory processes. Since atherosclerosis…
Six rapid assessments of alcohol and other substance use in populations displaced by conflict
Abstract Background: Substance use among populations displaced by conflict is a neglected area of public health. Alcohol, khat, benzodiazepine, opiate,…
Anti-emetic drugs in oncology: pharmacology and individualization by pharmacogenetics
Abstract Objective Nausea and vomiting are the most distressful side effects of cytotoxic drugs in cancer patients. Antiemetics are commonly…
Cannabidiol reduces lipopolysaccharide-induced vascular changes and inflammation in the mouse brain: an intravital microscopy study
Abstract Background: The phytocannabinoid cannabidiol (CBD) exhibits antioxidant and antiinflammatory properties. The present study was designed to explore its effects…
Drug-Induced Psychosis: How to Avoid Star Gazing in Schizophrenia Research by Looking at More Obvious Sources of Light
Abstract The prevalent view today is that schizophrenia is a syndrome rather than a specific disease. Liability to schizophrenia is…
Neuropharmacological properties of Mikania scandens (L.) Willd. (Asteraceae)
Abstract Mikania scandens (L.) Willd. (Asteraceae), known as climbing hemp weed in English, is a herbaceous climbing vine grown as…
Endocannabinoid system in cardiovascular disorders – new pharmacotherapeutic opportunities
Abstract The long history of Cannabis sativa had its development stimulated and oriented for medicine after the discovery and chemical…