Sexually Dimorphic Effects of Cannabinoid Compounds on Emotion and Cognition
Abstract This review addresses the issue of sex differences in the response to cannabinoid compounds focusing mainly on behaviors belonging…
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Beyond THC: The New Generation of Cannabinoid Designer Drugs
Abstract Synthetic cannabinoids are functionally similar to delta9-tetrahydrocannabinol (THC), the psychoactive principle of cannabis, and bind to the same cannabinoid…
Acute Effects of Delta-9-Tetrahydrocannabinol on Performance Monitoring in Healthy Volunteers
Abstract Rationale: The error-related negativity (ERN) is a negative event-related potential that occurs immediately after an erroneous response and is…
Effects of Endocannabinoid System Modulation on Cognitive and Emotional Behavior
Abstract Cannabis has long been known to produce cognitive and emotional effects. Research has shown that cannabinoid drugs produce these…
Current and emerging “at-site” pain medications: a review
Abstract The myriad pain pathophysiology has intrigued and challenged humanity for centuries. In this regard, the traditional pain therapies such…
Increased Expression of Cannabinoid CB1 Receptors in Achilles Tendinosis
Abstract Background: The endogenous cannabinoid system is involved in the control of pain. However, little is known as to the…
Aryl hydrocarbon receptor-dependent upregulation of Cyp1b1 by TCDD and diesel exhaust particles in rat brain microvessels
Abstract Background: AhR activates the transcription of several target genes including CYP1B1. Recently, we showed CYP1B1 as the major cytochrome…
The Endocannabinoid System as Pharmacological Target Derived from Its CNS Role in Energy Homeostasis and Reward. Applications in Eating Disorders and Addiction
Abstract The endocannabinoid system (ECS) has been implicated in many physiological functions, including the regulation of appetite, food intake and…
Involvement of the endocannabinoid system in reward processing in the human brain
Abstract Rationale: Disturbed reward processing in humans has been associated with a number of disorders, such as depression, addiction, and…
Impact of environmental factors on marijuana use in 11 European countries
Abstract Aim: To investigate the association between environmental factors (perceived availability of marijuana, perceived use among friends and siblings, use…