On the impact of batch effect correction in TCGA isomiR expression data
Abstract MicroRNAs (miRNAs) are small non-coding RNAs with diverse functions in post-transcriptional regulation of gene expression. Sequence and length variants…
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Cannabidiol Inhibits SARS-CoV-2 Replication and Promotes the Host Innate Immune Response
Abstract The rapid spread of COVID-19 underscores the need for new treatments. Here we report that cannabidiol (CBD), a compound…
Marijuana: A systems-based primer of adverse effects associated with use and an overview of its therapeutic utility
Abstract Marijuana use is on the rise in the United States. By the end of 2019, 33 states have legalized…
Morbidity and mortality in schizophrenia with comorbid substance use disorders
Abstract Objective: Schizophrenia is highly comorbid with substance use disorders (SUD) but large epidemiological cohorts exploring the prevalence and prognostic…
Electronic Vaping-Induced Methicillin-Sensitive Staphylococcus Aureus Pneumonia and Empyema
Abstract Pneumonia is a severe acute inflammation of the lower respiratory tract due to infectious pathogens. Pathogens responsible include bacteria,…
Assessment of Annual Cost of Substance Use Disorder in US Hospitals
Abstract Question: How much does substance use disorder cost each year in US hospitals? Findings: In this economic evaluation of…
Investigating the Factors Affecting the Development of Biliary Pancreatitis and Their Relationship with the Type and Severity of Complications
Abstract BACKGROUND Pancreatitis is an inflammation of the pancreatic tissue. Gallstones are known to be the most common cause of…
Predictive factors affecting percutaneous drainage duration in the percutaneous treatment of common bile duct stones
Abstract The duration of percutaneous transhepatic biliary drainage (PTBD) is a critical factor that determines the duration of treatment. This…
The Therapeutic Potential and Usage Patterns of Cannabinoids in People with Spinal Cord Injuries: A Systematic Review
Abstract Background: People with spinal cord injuries (SCI) commonly experience pain and spasticity; limitations of current treatments have generated interest…
Targeting the Endocannabinoid System in Borderline Personality Disorder: Corticolimbic and Hypothalamic Perspectives
Abstract Borderline Personality Disorder (BPD) is a chronic debilitating psychiatric disorder characterized mainly by emotional instability, chaotic interpersonal relationships, cognitive…