Cannabidiol counters the effects of a dominant-negative pathogenic Kv7.2 variant
Abstract Epilepsy and neurodevelopmental disorders can arise from pathogenic variants of KCNQ (Kv7) channels. A patient with developmental and epileptic…
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Person-centered patterns of substance use during the COVID-19 pandemic and their associations with COVID-related impacts on health and personal finances in young Black and White women
Abstract Background: Population-level statistics on pandemic-related change in substance use can obscure patterns of use (e.g., polysubstance use) within individuals.…
Endocannabinoid-dependent formation of columnar axonal projection in the mouse cerebral cortex
Abstract One of the most important morphological properties in the cerebral cortex is the columnar structure, where axonal projections occur…
Medical students’ perception and academic performance after team-based and seminar-based learning in human anatomy
Abstract Objectives: Student-centered educational strategies like problem-based learning (PBL), case-based learning (CBL), team-based learning (TBL), and seminars enhance group and…
The effect of combining basil seeds and gum Arabic on the healing process of experimental acetic acid-induced ulcerative colitis in rats
Abstract Background & aim: Ulcerative colitis (UC) is a chronic recurrent inflammatory disease of the large intestine and rectum that…
Collagen-binding vascular endothelial growth factor (CBD-VEGF) promotes liver regeneration in murine partial hepatectomy
Abstract Liver regeneration is a complex process that needs orchestration of multiple nonparenchymal cells including sinusoid endothelial cells. Vascular endothelial…
A sesquiterpene isolated from the stems and leaves of Dioscorea opposita thunb. Transforms the composition of immune cells through ERβ in a mouse model of LPS-induced lung injury
Abstract Acute lung injury (ALI) is a common critical disease with a high mortality rate. Natural products have marked efficacy…
Factors Associated with Problematic Cannabis Use in a Sample of Medical Cannabis Dispensary Users
Abstract Background: With the recent legalization of cannabis for medical purposes in many countries, there has been an increased number…
Prevalence of cannabis use disorder among pregnant people who test positive for cannabis at time of delivery
Abstract BACKGROUND: Cannabis use in pregnancy is common, but the reasons that some pregnant people continue use are unclear. OBJECTIVE:…
Cannabidiol Modulating the Expression of Neurotrophin Signaling Pathways in Chronic Exposure to Methamphetamine in Rats During Abstinence Period
Abstract Introduction: Several neuropsychiatric disorders, such as addiction, have indicated variations in the levels of neurotrophic factors. As an extremely…