Gastroparesis: Myths, Misconceptions, and Management
Abstract Gastroparesis (GP), a historically vexing disorder characterized by symptoms of nausea, vomiting, abdominal pain, early satiety, and/or bloating, in…
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Substance Use Disorders in the Geriatric Population: a Review and Synthesis of the Literature of a Growing Problem in a Growing Population
Abstract Purpose of review: Substance use disorders are becoming increasingly prevalent in the geriatric population, necessitating an updated understanding of…
Pre-puberty cannabichromene exposure modulates reproductive function via alteration of spermatogenesis, steroidogenesis, and eNOS pathway metabolites
Abstract Background: Cannabis and cannabinoids affect almost every system of the body and exert systemic effects such as alterations in…
Synthetic and Medicinal Chemistry Approaches Toward WEE1 Kinase Inhibitors and Its Degraders
Abstract WEE1 is a checkpoint kinase critical for mitotic events, especially in cell maturation and DNA repair. Most cancer cells’…
Toxicological safety assessment of HempChoice® hemp oil extract; a proprietary extract consisting of a high concentration of cannabidiol (CBD) in addition to other phytocannabinoids and terpenes derived from CannabissativaL
Abstract HempChoice® Hemp Oil Extract (Geocann, LLC) is an extract of the aerial parts of hemp (Cannabis sativa L.) primarily…
Frailty as a risk-stratification tool in patients undergoing transjugular intrahepatic portosystemic shunt (TIPS)
Abstract Objectives: The concept of frailty has gained importance, especially in patients with liver disease. Our study systematically investigated the…
Uso de sustancias psicoactivas como tratamiento de la psicosis
Abstract Introducción.: Los trastornos psicóticos se consideran problemas crónicos de salud mental. Aunque se ha demostrado que estos trastornos pueden…
Twitter activity surrounding the Finnish green party’s cannabis legalisation proposal: A mixed-methods analysis
Abstract Background: In September 2021, a Finnish political party, the Greens, voted to include cannabis policy reform in their party…
Cannabidiol-Decorated Berberine-Loaded Microemulsions Improve IBS-D Therapy Through Ketogenic Diet-Induced Cannabidiol Receptors Overexpression
Abstract Background: Berberine (BR) shows promise as a candidate for treating irritable bowel syndrome with diarrhea (IBS-D). However, the undesired…
Multi-Omics Analysis and Verification of the Oncogenic Value of CCT8 in Pan-Cancers
Abstract Background: Chaperonin-containing TCP1 subunit 8 (CCT8) has been proved to be involved in the occurrence and development of some…