Substance Use in Pregnancy and its Association With Cardiovascular Events
Abstract Background: Substance use and cardiovascular (CV) events are increasing among pregnant women in the United States, but association between…
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Inhibitory activity of lignanamides isolated from hemp seed hulls(Cannabis sativa L.) against soluble epoxide hydrolase
Abstract Soluble epoxide hydrolase (sEH) is a therapeutic target for inflammation. In the present study, we isolated one new (1)…
Reverse Mirizzi Syndrome
Abstract A man in his 40s presented to our Hospital with abdominal pain, jaundice, and pruritus. He had a history…
Patients’ perspectives on marijuana use for inflammatory bowel disease: a multicenter survey
Abstract Background: As marijuana use is rising among patients with inflammatory bowel disease (IBD), so is interest in its potential…
Pan-Cancer Analysis of Oncogenic Role of RAD54L and Experimental Validation in Hepatocellular Carcinoma
Abstract Background: RAD54L is a prominent member of the SWI2/SNF2 protein family, primarily involved in the homologous recombination repair (HRR)…
The diagnostic or prognostic values of FADD in cancers based on pan‑cancer analysis
Abstract Previous studies have determined that aberrant expression of the fas-associated death domain (FADD) contributes to the development of cancer.…
Pharmacotherapy for Dravet Syndrome: A Systematic Review and Network Meta-Analysis of Randomized Controlled Trials
Abstract Background: Dravet syndrome (DS) is a severe developmental and epileptic encephalopathy characterized by drug-resistant, lifelong seizures. The management of…
Association between cannabis use and symptom dimensions in schizophrenia spectrum disorders: an individual participant data meta-analysis on 3053 individuals
Abstract Background: The association between cannabis use and positive symptoms in schizophrenia spectrum disorders is well documented, especially via meta-analyses.…
A comparative analysis of graduate preparedness for a career in General Internal Medicine before and after national subspecialty recognition to inform curricular changes: have we met the mark?
Abstract Background: A survey of General Internal Medicine (GIM) graduates published in 2006 revealed large training gaps that informed the…
Cannabis Use: A New Risk Behaviour Among Adults With Congenital Heart Disease
Abstract Background: Cannabis use has increased in Canada and can be associated with adverse cardiovascular events. Given increased use and…