Comprehensive pan-cancer analysis of FSCN1 as a marker for prognosis and immunity
Abstract Background: Fascin actin-bundling protein 1 (FSCN1), a member of actin cytoskeletal protein family genes, plays critical roles in cell…
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Cell-cycle targeted cancer therapy: clinical advances, biological gaps, and the emergence of selective CDK4 inhibitors
Abstract Cyclin-dependent kinase (CDK) 4/6 inhibitors have reshaped the therapeutic landscape for hormone receptor (HR)-positive breast cancer and firmly established…
Effect of cannabinol, tetrahydrocannabivarin and cannabidiol on voluntary alcohol consumption
Abstract Aims: Previous studies have demonstrated that the endocannabinoid system plays a significant role in the development of alcohol use…
Evaluating a digital serious game for learning medical terminology in a randomized controlled trial
Abstract Healthcare students often struggle with learning medical terminology due to its complexity and abstract nature. This randomized controlled trial…
A Male Mouse Model of WIN 55,212–2 Self-Administration to Study Cannabinoid Addiction
Abstract Despite substantial progress in preclinical cannabinoid research, translational studies on cannabis use disorders (CUD) are still insufficient due to…
Multi-omics analysis reveals the role of the XRCC gene family in diagnosis, prognosis, and immunity in pan-cancer
Abstract Supplementary Information: The online version contains supplementary material available at 10.1007/s12672-026-04693-y. Article type: Research Article Keywords: XRCC family, Pan-cancer,…
Nose-to-brain administration of cannabidiol-loaded polymeric micelles improves the core behavioral symptoms of autism spectrum disorder
Abstract Neurodevelopmental disorders including autism spectrum disorder (ASD) affect 5.9% of the global population. Research shows the potential therapeutic use…
Ballistic and drop-weight impact response of SS304 metal mesh embedded woven flax/hemp fiber hybrid composites
Abstract This research looks over the way hybrid natural fiber composites reinforced with woven SS304 wire mesh and flax-hemp yarns…
Seeing differently: (De)Constructing cultural narratives of blindness in al-Kīt Kāt and Scent of a Woman
Abstract While disability studies have significantly evolved over the past few decades, cinematic representations of people with disabilities, particularly in…
Cannabis use among cancer survivors: a systematic review and meta-analysis
Abstract Introduction: The use of medical cannabis has been receiving growing attention as a potential therapeutic option for a diverse…