Pan-cancer analysis and mechanistic insights of tuft cell-like tumors
Abstract Tuft cells are rare, chemosensory epithelial cells present in various tissues, including the respiratory and gastrointestinal tracts. Recent studies…
Free
The role of natural compounds in modulation of small extracellular vesicle biogenesis and lipid metabolism in cancer
Abstract Small extracellular vesicles (sEVs) are vesicles of 15–150 nm in diameter secreted by cells and contain biological compounds that…
Medical cannabis in Israel: a comprehensive review of trends and regulations, 2011–2025
Abstract Background: Since its initial approval in 1992, medical cannabis (MC) in Israel has undergone extensive regulatory and structural transformation.…
Chemical Profile, Bioactive Constituents and In Vitro Growth Stimulation Properties of Cold-Pressed Hemp Seed Oils from Romanian Varieties: In Vitro and In Silico Evaluation
Abstract Industrial hemp (Cannabis sativa L.; Cannabaceae), traditionally cultivated for fiber, also represents a valuable source of nutrient-rich seed oil.…
Multifaced roles of cannabinoid therapy in cancer: balancing analgesia, antitumor potential, and systemic toxicity
Abstract Introduction: Cannabinoids hold promise in oncology for symptom relief and antitumor effects, though concerns about safety and efficacy persist.…
Influence of Agronomic Practices on the Bioactive Compound Production in Cannabis sativa L.
Abstract Industrial hemp phytochemistry is shaped by genetics and agronomic management, yet field studies integrating both remain scarce. The combined…
Identifying Stigma Phenotypes in Social Media Narratives of Substance Use: Observational Study
Abstract Background: Individuals with substance use problems experience stigma in different contexts. Identifying characteristic situations in which stigma occurs or…
Verbal memory dysfunction in substance use and gambling addictive disorders: a comparative analysis of performance accuracy and error typologies
Abstract Addiction is increasingly recognized as a disorder involving not only reward dysregulation but also alterations in core cognitive processes,…
Per Se Driving Under the Influence of Cannabis Statutes and Blood Delta-9-Tetrahydrocannabinol Concentrations following Short-Term Cannabis Abstinence
Abstract Background: Several US states have per se laws using 2 or 5 ng/mL of delta-9-tetrahydrocannabinol (THC) as cutpoints for…
3D-Printed Alginate–Chitosan Hydrogel Loaded with Cannabidiol as a Platform for Drug Delivery: Design and Mechanistic Characterization
Abstract Alginate and chitosan (Ag/Cs) combined form an effective platform to develop biocompatible hydrogels with customizable properties for controlled drug…