Attenuation of Listeria monocytogenes Virulence by Cannabis sativa L. Essential Oil
Abstract Anti-virulence strategies are being explored as a novel approach to combat pathogens. Such strategies include inhibition of surface adhesion,…
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Cannabidiol Administered During Peri-Adolescence Prevents Behavioral Abnormalities in an Animal Model of Schizophrenia
Abstract Schizophrenia is considered a debilitating neurodevelopmental psychiatric disorder and its pharmacotherapy remains problematic without recent major advances. The development…
Traditional Uses of Cannabinoids and New Perspectives in the Treatment of Multiple Sclerosis
Abstract Recent findings highlight the emerging role of the endocannabinoid system in the control of symptoms and disease progression in…
Self-Reported Effectiveness and Safety of Trokie® Lozenges: A Standardized Formulation for the Buccal Delivery of Cannabis Extracts
Abstract Therapeutic use of cannabinoids, the main active ingredients of Cannabis sativa L., is often hindered by their limited bioavailability…
Cannabidiol (CBD) Is a Novel Inhibitor for Exosome and Microvesicle (EMV) Release in Cancer
Abstract Exosomes and microvesicles (EMV) are lipid bilayer-enclosed structures, released by cells and involved in intercellular communication through transfer of…
Anti-stress neuropharmacological mechanisms and targets for addiction treatment: A translational framework
Abstract Stress-related substance use is a major challenge for treating substance use disorders. This selective review focuses on emerging pharmacotherapies…
Antioxidant Potential of Hemp and Flax Fibers Depending on Their Chemical Composition
Abstract Flax and hemp fibers are known as textile raw materials with pro-health properties. This paper presents results of research…
Treatment of Periodontal Ligament Stem Cells with MOR and CBD Promotes Cell Survival and Neuronal Differentiation via the PI3K/Akt/mTOR Pathway
Abstract Periodontal ligament mesenchymal stem cells (hPDLSCs), as well as all mesenchymal stem cells, show self-renewal, clonogenicity, and multi-tissue differentiation…
Cannabis Legalization in Canada: Reflections on Public Health and the Governance of Legal Psychoactive Substances
Abstract The Canadian government is “taking a public health approach to legalizing, strictly regulating and restricting access to cannabis.” There…
Cannabidiol Attenuates Experimental Autoimmune Encephalomyelitis Model of Multiple Sclerosis Through Induction of Myeloid-Derived Suppressor Cells
Abstract Multiple sclerosis (MS) is a chronic debilitating autoimmune disease without a cure. While the use of marijuana cannabinoids for…