A Review of Herbal Therapy in Multiple Sclerosis
Abstract Multiple sclerosis is a complex autoimmune disorder which characterized by demyelination and axonal loss in the central nervous system…
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The Effects of Substance Abuse on Blood Glucose Parameters in Patients with Diabetes: A Systematic Review and Meta-Analysis
Abstract Background: People who abuse substances are at increased risk of metabolic syndrome and diabetes resulting partly from increased cell…
Brain-Derived Neurotrophic Factor (BDNF) Role in Cannabinoid-Mediated Neurogenesis
Abstract The adult mammalian brain can produce new neurons in a process called adult neurogenesis, which occurs mainly in the…
Broad and Region-Specific Impacts of the Synthetic Cannabinoid CP 55,940 in Adolescent and Adult Female Mouse Brains
Abstract Relative to Δ9-tetrahydrocannabinol (THC), the synthetic cannabinoid CP 55,940 (CP) is significantly more potent and efficacious at cannabinoid receptors,…
Pharmacological management of cachexia in adult cancer patients: a systematic review of clinical trials
Abstract Background: Cachexia is a multisystem syndrome characterized by weight loss, anorexia, loss of muscle mass, systemic inflammation, insulin resistance,…
CB1 Agonism Alters Addiction-Related Behaviors in Mice Lacking Mu or Delta Opioid Receptors
Abstract Opioids are powerful analgesics but the clinical utility of these compounds is reduced by aversive outcomes, including the development…
A Systematic Review on the Pharmacokinetics of Cannabidiol in Humans
Abstract Background: Cannabidiol is being pursued as a therapeutic treatment for multiple conditions, usually by oral delivery. Animal studies suggest…
∆9-Tetrahydrocannabinol, a major marijuana component, enhances the anesthetic effect of pentobarbital through the CB1 receptor
Abstract Purpose: ∆9–Tetrahydrocannabinol (∆9-THC) and cannabidiol (CBD), major psychoactive constituents of marijuana, induce potentiation of pentobarbital-induced sleep in mice. We…
Optimizing Hemp Fiber Production for High Performance Composite Applications
Abstract Hemp is a sustainable and environmental friendly crop that can provide valuable raw materials to a large number of…
Synergistic effect of fruit–seed mixed juice on inhibition of angiotensin I-converting enzyme and activation of NO production in EA.hy926 cells
Abstract Commonly consumed fruit juices possess low inhibitory activity of angiotensin I-converting enzyme (ACE), which plays central role in elevation…