The Interplay between the Endocannabinoid System, Epilepsy and Cannabinoids
Abstract Epilepsy is a neurological disorder that affects approximately 50 million people worldwide. There is currently no definitive epilepsy cure.…
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Transient Receptor Potential Cation Channels in Cancer Therapy
Abstract In mammals, the transient receptor potential (TRP) channels family consists of six different families, namely TRPC (canonical), TRPV (vanilloid),…
Transcriptomic Analysis of Stem Cells Treated with Moringin or Cannabidiol: Analogies and Differences in Inflammation Pathways
Abstract Inflammation is a common feature of many neurodegenerative diseases. The treatment of stem cells as a therapeutic approach to…
Characteristics of E-cigarette, or Vaping, Products Used by Patients with Associated Lung Injury and Products Seized by Law Enforcement — Minnesota, 2018 and 2019
Authors: Joanne Taylor, Terra Wiens, Jason Peterson, Stefan Saravia, Mark Lunda, Kaila Hanson, Matt Wogen, Paige D’Heilly, Jamie Margetta, Maria…
Pharmacologic and Non-Pharmacologic Interventions for HIV-Neuropathy Pain. A Systematic Review and a Meta-Analysis
Abstract Background and Objectives: Among HIV infection symptoms, sensory neuropathy (HIV-SN) remains a main cause of suffering, with incidence varying…
Cannabidiol—from Plant to Human Body: A Promising Bioactive Molecule with Multi-Target Effects in Cancer
Abstract Cannabis sativa L. is a plant long used for its textile fibers, seed oil, and oleoresin with medicinal and…
The Endocannabinoid System in Pediatric Inflammatory and Immune Diseases
Abstract Endocannabinoid system consists of cannabinoid type 1 (CB1) and cannabinoid type 2 (CB2) receptors, their endogenous ligands, and the…
Use of Fermented Hemp, Chickpea and Milling By-Products to Improve the Nutritional Value of Semolina Pasta
Abstract A biotechnological approach including enzymatic treatment (protease and xylanase) and lactic acid bacteria fermentation has been evaluated to enhance…
Allosteric Modulation of Cannabinoid Receptor 1—Current Challenges and Future Opportunities
Abstract The cannabinoid receptor type 1 (CB1R), a G protein-coupled receptor (GPCR), plays an essential role in the control of…
Structure–Effect Relationships of Novel Semi-Synthetic Cannabinoid Derivatives
Abstract Background: As a library of cannabinoid (CB) derivatives with (-)-trans-cannabidiol (CBD) or (-)-trans-cannabidivarin (CBDV) scaffold, we synthesized nine novel…