Cannabinoids in the Older Person: A Literature Review
Abstract Introduction: Medical cannabinoids have received significant mainstream media attention in recent times due to an evolving political and clinical…
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Neuroprotective and Neuromodulatory Effects Induced by Cannabidiol and Cannabigerol in Rat Hypo-E22 cells and Isolated Hypothalamus
Abstract Background: Cannabidiol (CBD) and cannabigerol (CBG) are non-psychotropic terpenophenols isolated from Cannabis sativa, which, besides their anti-inflammatory/antioxidant effects, are…
Cannabinoid Receptor 2 Modulates Maturation of Dendritic Cells and Their Capacity to Induce Hapten-Induced Contact Hypersensitivity
Abstract Contact hypersensitivity (CHS) is an established animal model for allergic contact dermatitis. Dendritic cells (DCs) play an important role…
Use of Herbal Medicine by Pregnant Women: What Physicians Need to Know
Abstract About 80% of the consumers worldwide use herbal medicine (HMs) or other natural products. The percentage may vary significantly…
Challenges and Opportunities in Preclinical Research of Synthetic Cannabinoids for Pain Therapy
Abstract Cannabis has been used in pain management since 2900 BC. In the 20th century, synthetic cannabinoids began to emerge,…
Effects of short-term cannabidiol treatment on response to social stress in subjects at clinical high risk of developing psychosis
Abstract Rationale: Stress is a risk factor for psychosis and treatments which mitigate its harmful effects are needed. Cannabidiol (CBD)…
Protein Deimination and Extracellular Vesicle Profiles in Antarctic Seabirds
Abstract Pelagic seabirds are amongst the most threatened of all avian groups. They face a range of immunological challenges which…
Associations between psychoactive substance use and sensation seeking behavior among drivers in Norway
Abstract Background/aim: Drug use and risky driving is associated with sensation seeking. The aim of this study was to investigate…
Acute human exposure assessment to tetrahydrocannabinol (Δ9‐THC)
Abstract Delta‐9‐tetrahydrocannabinol (Δ9‐THC) is a naturally occurring psychoactive compound derived from the hemp plant Cannabis sativa. In 2015, EFSA established…
Buprenorphine–cannabis interaction in patients undergoing opioid maintenance therapy
Abstract Buprenorphine is a partial μ-opioid agonist widely used for opioid maintenance therapy (OMT). It is mainly metabolized to pharmacologically…