Influence of Altitude on Phytochemical Composition of Hemp Inflorescence: A Metabolomic Approach
Abstract The phytochemical profiling of hemp inflorescences of clonal plants growing in different conditions related to altitude was investigated. Four…
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Neurobiological Trajectories Involving Social Isolation in PTSD: A Systematic Review
Abstract Social isolation (SI) stress has been recognized as a major risk factor of morbidity in humans and animals, exerting…
Effects of dietary hemp seed oil to sows on fatty acid profiles, nutritional and immune status of piglets
Abstract Background: The oil from industrial hemp seeds (Cannabis sativa) is an ideal source of stearidonic acid, which is a…
Time- and temperature-dependent postmortem concentration changes of the (synthetic) cannabinoids JWH-210, RCS-4, as well as ∆9-tetrahydrocannabinol following pulmonary administration to pigs
Abstract In forensic toxicology, interpretation of postmortem (PM) drug concentrations might be complicated due to the lack of data concerning…
The Broad Concept of “Spasticity-Plus Syndrome” in Multiple Sclerosis: A Possible New Concept in the Management of Multiple Sclerosis Symptoms
Abstract Multiple sclerosis (MS) pathology progressively affects multiple central nervous system (CNS) areas. Due to this fact, MS produces a…
Cannabidiol (CBD) Inhibited Rhodamine-123 Efflux in Cultured Vascular Endothelial Cells and Astrocytes Under Hypoxic Conditions
Abstract Despite the constant development of new antiepileptic drugs (AEDs), more than 30% of patients develop refractory epilepsy (RE) characterized…
Urban wastewater analysis as an effective tool for monitoring illegal drugs, including new psychoactive substances, in the Eastern European region
Abstract The use of illicit drugs causes unquestionable societal and economic damage. To implement actions aimed at combating drug abuse,…
Cannabinoids, Blood–Brain Barrier, and Brain Disposition
Abstract Potential therapeutic actions of the cannabinoids delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD) are based on their activity as analgesics, anti-emetics,…
Selective Extraction of Cannabinoid Compounds from Cannabis Seed Using Pressurized Hot Water Extraction
Abstract Phytochemicals of Cannabis sativa mainly for the use in the different industries are that of delta-9-tetrahydrocannabinol (THC) and cannabidiol…
Efficacy of Dronabinol for Acute Pain Management in Adults with Traumatic Injury: Study Protocol of A Randomized Controlled Trial
Abstract Delta-9-tetrahydrocannabinol (Δ9-THC) and other cannabinoids present in cannabis (marijuana) have been shown to affect the normal inhibitory pathways that…