Effects of ∆9-tetrahydrocannabinol on aversive memories and anxiety: a review from human studies
Abstract Background: Posttraumatic stress disorder (PTSD) may stem from the formation of aberrant and enduring aversive memories. Some PTSD patients…
Free
Chronic Cannabidiol Administration Attenuates Skeletal Muscle De Novo Ceramide Synthesis Pathway and Related Metabolic Effects in a Rat Model of High-Fat Diet-Induced Obesity
Abstract Numerous studies showed that sustained obesity results in accumulation of bioactive lipid derivatives in several tissues, including skeletal muscle,…
Links between central CB1-receptor availability and peripheral endocannabinoids in patients with first episode psychosis
Abstract There is an established, link between psychosis and metabolic abnormalities, such as altered glucose metabolism and dyslipidemia, which often…
Is the Adolescent Brain at Greater Vulnerability to the Effects of Cannabis? A Narrative Review of the Evidence
Abstract Cannabis use during the critical neurodevelopmental period of adolescence, may lead to brain structural, functional, and histological alterations that…
Oral Transmucosal Cannabidiol Oil Formulation as Part of a Multimodal Analgesic Regimen: Effects on Pain Relief and Quality of Life Improvement in Dogs Affected by Spontaneous Osteoarthritis
Abstract Simple Summary: Osteoarthritis is a progressive and degenerative condition that affects dog populations, causing pain. The pain associated with…
Molecular Pharmacology of Synthetic Cannabinoids: Delineating CB1 Receptor-Mediated Cell Signaling
Abstract Synthetic cannabinoids (SCs) are a class of new psychoactive substances (NPSs) that exhibit high affinity binding to the cannabinoid…
Evidence of Slow Neural Processing, Developmental Differences and Sensitivity to Cannabis Effects in a Sample at Clinical High Risk for Psychosis From the NAPLS Consortium Assessed With the Human Startle Paradigm
Abstract Abstract: Biomarkers are important in the study of the prodromal period of psychosis because they can help to identify…
Quantitative determination and validation of 17 cannabinoids in cannabis and hemp using liquid chromatography-tandem mass spectrometry
Abstract Electronic supplementary material: The online version of this article (10.1007/s00216-020-02862-8) contains supplementary material, which is available to authorized users.…
Isomeric O-methyl cannabidiolquinones with dual BACH1/NRF2 activity
Abstract Oxidative stress and inflammation in the brain are two key hallmarks of neurodegenerative diseases (NDs) such as Alzheimer’s, Parkinson’s,…
Roles of Cannabinoids in Melanoma: Evidence from In Vivo Studies
Abstract Melanoma is the fourth most common type of cancer diagnosed in Australians after breast, prostate, and colorectal cancers. While…