Cannabidiol in Pharmacoresistant Epilepsy: Clinical Pharmacokinetic Data From an Expanded Access Program
Abstract Background and Aim: Data on the clinical pharmacokinetics of cannabidiol (CBD) are scanty. We explored the effect of demographic…
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THC Reduces Ki67-Immunoreactive Cells Derived from Human Primary Glioblastoma in a GPR55-Dependent Manner
Abstract Simple Summary: Glioblastoma (GBM) is the most frequent primary brain tumor entity with poor prognosis and resistance to current…
Diretrizes Brasileiras de Hipertensão Arterial – 2020
Authors: Weimar Kunz Sebba Barroso ⚬, Cibele Isaac Saad Rodrigues ⚬, Luiz Aparecido Bortolotto ⚬, Marco Antônio Mota-Gomes ⚬, Andréa…
Characterization of Estrogenic Activity and Site-Specific Accumulation of Bisphenol-A in Epididymal Fat Pad: Interfering Effects on the Endocannabinoid System and Temporal Progression of Germ Cells
Abstract The objective of this work has been to characterize the estrogenic activity of bisphenol-A (BPA) and the adverse effects…
Vibrational Spectroscopic Analyses and Imaging of the Early Middle Ages Hemp Bast Fibres Recovered from Lake Sediments
Abstract Fourier Transform Infrared (FT-IR) spectroscopy and imaging combined with hierarchical cluster analysis (HCA) was applied to analyse biochemical properties…
Cannabinoids, reward processing, and psychosis
Abstract Background: Evidence suggests that an overlap exists between the neurobiology of psychotic disorders and the effects of cannabinoids on…
Regulatory status of pesticide residues in cannabis: Implications to medical use in neurological diseases
Abstract Movement disorders are the most common neurological category of qualifying conditions in the U.S. The number and action levels…
The Biochemistry of Phytocannabinoids and Metabolic Engineering of Their Production in Heterologous Systems
Abstract The medicinal properties of cannabis and the its legal status in several countries and jurisdictions has spurred the massive…
Emerging diseases of Cannabis sativa and sustainable management
Abstract Cultivation of cannabis plants (Cannabis sativa L., marijuana) has taken place worldwide for centuries. In Canada, legalization of cannabis…
Cannabinoid-Induced Conditioned Place Preference, Intravenous Self-Administration, and Behavioral Stimulation Influenced by Ghrelin Receptor Antagonism in Rats
Abstract Cannabis/cannabinoids are widely used for recreational and therapy purposes, but their risks are largely disregarded. However, cannabinoid-associated use disorders…