The biosynthesis of the cannabinoids
Abstract Abstract: Cannabis has been integral to Eurasian civilization for millennia, but a century of prohibition has limited investigation. With…
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The frequency distribution of reported THC concentrations of legal cannabis flower products increases discontinuously around the 20% THC threshold in Nevada and Washington state
Abstract Background: Cannabis laboratory testing reliability is a scientific and policy challenge in US states with legal cannabis. Greater reported…
Development of a Novel Microwave Distillation Technique for the Isolation of Cannabis sativa L. Essential Oil and Gas Chromatography Analyses for the Comprehensive Characterization of Terpenes and Terpenoids, Including Their Enantio-Distribution
Abstract A microwave distillation method was optimized for the extraction and isolation of cannabis essential oil from fresh and dried…
Prospects for the Use of Cannabinoids in Psychiatric Disorders
Abstract Increasing evidence suggests an essential role of the endocannabinoid system in modulating cognitive abilities, mood, stress, and sleep. The…
Duration of Neurocognitive Impairment With Medical Cannabis Use: A Scoping Review
Abstract While the recreational use of cannabis has well-established dose-dependent effects on neurocognitive and psychomotor functioning, there is little consensus…
Multispecies Identification of Oilseed- and Meat-Specific Proteins and Heat-Stable Peptide Markers in Food Products
Abstract Consumer demand for both plant products and meat products enriched with plant raw materials is constantly increasing. Therefore, new…
Endocannabinoid and dopaminergic system: the pas de deux underlying human motivation and behaviors
Abstract Endocannabinoid system (ECS) has been identified ever since cannabinoid, an active substance of Cannabis, was known to interact with…
Overcoming Glucocorticoid Resistance in Acute Lymphoblastic Leukemia: Repurposed Drugs Can Improve the Protocol
Abstract Glucocorticoids (GCs) are a central component of multi-drug treatment protocols against T and B acute lymphoblastic leukemia (ALL), which…
Effects of Cannabidiol and Beta-Caryophyllene Alone or in Combination in a Mouse Model of Permanent Ischemia
Abstract Current treatments for stroke, which account for 6.5 million global deaths annually, remain insufficient for treatment of disability and…
Cannabidiol attenuates pulmonary arterial hypertension by improving vascular smooth muscle cells mitochondrial function
Abstract Rationale: Pulmonary arterial hypertension (PAH) is a chronic disease associated with enhanced proliferation of pulmonary artery smooth muscle cells…