Cell Therapy for Anal Sphincter Incontinence: Where Do We Stand?
Abstract Anal sphincter incontinence is a chronic disease, which dramatically impairs quality of life and induces high costs for the…
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The GPR18 Agonist PSB-KD-107 Exerts Endothelium-Dependent Vasorelaxant Effects
Abstract GPR18 is an orphan GPCR that is activated by the cannabinoid tetrahydrocannabinol (THC). Emerging evidence indicates its involvement in…
Changes in Phospholipid/Ceramide Profiles and Eicosanoid Levels in the Plasma of Rats Irradiated with UV Rays and Treated Topically with Cannabidiol
Abstract Chronic UV radiation causes oxidative stress and inflammation of skin and blood cells. Therefore, in this study, we assessed…
Efficacy and Safety of Cannabidiol Plus Standard Care vs Standard Care Alone for the Treatment of Emotional Exhaustion and Burnout Among Frontline Health Care Workers During the COVID-19 Pandemic
Abstract Question: Is cannabidiol (CBD) therapy capable of reducing emotional exhaustion and burnout symptoms among frontline health care professionals working…
Tamoxifen Sensitizes Acute Lymphoblastic Leukemia Cells to Cannabidiol by Targeting Cyclophilin-D and Altering Mitochondrial Ca2+ Homeostasis
Abstract Cytotoxic effects of cannabidiol (CBD) and tamoxifen (TAM) have been observed in several cancer types. We have recently shown…
Recalcitrance of Cannabis sativa to de novo regeneration; a multi-genotype replication study
Abstract Cannabis sativa is relatively recalcitrant to de novo regeneration, but several studies have reported shoot organogenesis or somatic embryogenesis…
Yield, Characterization, and Possible Exploitation of Cannabis Sativa L. Roots Grown under Aeroponics Cultivation
Abstract Cannabis sativa L. has been used for a long time to obtain food, fiber, and as a medicinal and…
Transient Receptor Potential (TRP) Ion Channels Involved in Malignant Glioma Cell Death and Therapeutic Perspectives
Abstract Among the most biologically, thus clinically, aggressive primary brain tumors are found malignant gliomas. Despite recent advances in adjuvant…
Genetic basis of cannabis use: a systematic review
Abstract Background: With the increase in cannabis use rates, cannabis use disorder is being reported as one of the most…
Female Community Health Workers and Health System Navigation in a Conflict Zone: The Case of Afghanistan
Abstract Afghanistan ranked 171st among 188 countries in the Gender Inequality Index of 2011 and has only 16% of its…