Cannabidiol modulation of hippocampal glutamate in early psychosis
Abstract Background: Emerging evidence supports the antipsychotic effect of cannabidiol, a non-intoxicating component of cannabis, in people with psychosis. Preclinical…
Free
The impact of state cannabis legislation, county-level socioeconomic and dog-level characteristics on reported cannabis poisonings of companion dogs in the USA (2009–2014)
Abstract With current trends in cannabis legalization, large efforts are being made to understand the effects of less restricted legislation…
Cannabis sativa terpenes are cannabimimetic and selectively enhance cannabinoid activity
Abstract Limited evidence has suggested that terpenes found in Cannabis sativa are analgesic, and could produce an “entourage effect” whereby…
Repurposing Cannabidiol as a Potential Drug Candidate for Anti-Tumor Therapies
Abstract In recent years, evidence has accumulated that cannabinoids—especially the non-psychoactive compound, cannabidiol (CBD)—possess promising medical and pharmacological activities that…
Fibroblast Growth Factor Signalling in the Diseased Nervous System
Abstract Fibroblast growth factors (FGFs) act as key signalling molecules in brain development, maintenance, and repair. They influence the intricate…
A systematic review of neuroimaging and acute cannabis exposure in age-of-risk for psychosis
Abstract Acute exposure to cannabis has been associated with an array of cognitive alterations, increased risk for neuropsychiatric illness, and…
Potential role of cannabidiol in Parkinson’s disease by targeting the WNT/β-catenin pathway, oxidative stress and inflammation
Abstract Parkinson’s disease (PD) is a major neurodegenerative disease (ND), presenting a progressive degeneration of the nervous system characterized by…
Plant-Origin Stabilizer as an Alternative of Natural Additive to Polymers Used in Packaging Materials
Abstract Over the past 25 years, cannabis plants have gained major popularity in the research community. This study aimed to…
Microglia Specific Drug Targeting Using Natural Products for the Regulation of Redox Imbalance in Neurodegeneration
Abstract Microglia, a type of innate immune cell of the brain, regulates neurogenesis, immunological surveillance, redox imbalance, cognitive and behavioral…
Ultra-High Performance Liquid Chromatography-High Resolution Mass Spectrometry and High-Sensitivity Gas Chromatography-Mass Spectrometry Screening of Classic Drugs and New Psychoactive Substances and Metabolites in Urine of Consumers
Abstract The use of the new psychoactive substances is continuously growing and the implementation of accurate and sensible analysis in…