Cannabidiol Isolated From Cannabis sativa L. Protects Intestinal Barrier From In Vitro Inflammation and Oxidative Stress
Abstract The relevance and incidence of intestinal bowel diseases (IBD) have been increasing over the last 50 years and the…
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Preclinical Advances in Theranostics for the Different Molecular Subtypes of Breast Cancer
Abstract Breast cancer is the most common cancer in women worldwide. The heterogeneity of breast cancer and drug resistance to…
Patients’ Experiences of a Nurse-Led, Home-Based Heart Failure Self-management Program: Findings From a Qualitative Process Evaluation
Abstract Background: Heart failure (HF) is a major public health problem that places a significant disease burden on society. Self-care…
The Endocannabinoid Anandamide Attenuates Acute Respiratory Distress Syndrome by Downregulating miRNA that Target Inflammatory Pathways
Abstract Acute respiratory distress syndrome (ARDS) is defined as a type of respiratory failure that is caused by a variety…
Pharmacotherapeutic Options for Managing Neuropathic Pain: A Systematic Review and Meta-Analysis
Abstract Despite an increasing number of available therapies, the treatment of neuropathic pain remains a major issue. Systematic reviews and…
Non-medical cannabis use: international policies and outcomes overview. An outline for Portugal
Abstract Introduction: Cannabis is probably the most commonly used illicit drug. It is often regarded as a relatively nonharmful experience,…
CBD, a precursor of THC in e-cigarettes
Abstract The use of cannabidiol (CBD) in electronic cigarettes is widespread. Previously, it was reported that CBD is partly transformed…
Peptide targeting of lysophosphatidylinositol-sensing GPR55 for osteoclastogenesis tuning
Abstract Background: The G-protein-coupled receptor GPR55 has been implicated in multiple biological activities, which has fuelled interest in its functional…
Development of Polylactic Acid Thermoplastic Starch Formulations Using Maleinized Hemp Oil as Biobased Plasticizer
Abstract In this study, hemp seed oil was reacted with maleic anhydride in an ene reaction to obtain maleinized hemp…
At the heart of microbial conversations: endocannabinoids and the microbiome in cardiometabolic risk
Abstract Cardiometabolic syndrome encompasses intertwined risk factors such as hypertension, dyslipidemia, elevated triglycerides, abdominal obesity, and other maladaptive metabolic and…