The Pathophysiology and the Therapeutic Potential of Cannabinoids in Prostate Cancer
Abstract Simple Summary: Prostate cancer, after lung cancer, is the leading cause of death among men. The incidence rate of…
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Healthy Lifestyle and Academic Performance in Middle School Students from the Region of Aragón (Spain)
Abstract A healthy lifestyle is important to the present and future development and health of school age people. This study…
Systematic review of the impact of cannabinoids on neurobehavioral outcomes in preclinical models of traumatic and nontraumatic spinal cord injury
Abstract Study design: Systematic review. Objectives: To evaluate the impact of cannabinoids on neurobehavioral outcomes in preclinical models of nontraumatic…
Cannabidiol versus risperidone for treatment of recent-onset psychosis with comorbid cannabis use: study protocol for a randomized controlled clinical trial
Abstract Background: Cannabis use is an important risk factor for development of psychosis and further transition to schizophrenia. The prevalence…
Cell Therapy for Anal Sphincter Incontinence: Where Do We Stand?
Abstract Anal sphincter incontinence is a chronic disease, which dramatically impairs quality of life and induces high costs for the…
The GPR18 Agonist PSB-KD-107 Exerts Endothelium-Dependent Vasorelaxant Effects
Abstract GPR18 is an orphan GPCR that is activated by the cannabinoid tetrahydrocannabinol (THC). Emerging evidence indicates its involvement in…
Changes in Phospholipid/Ceramide Profiles and Eicosanoid Levels in the Plasma of Rats Irradiated with UV Rays and Treated Topically with Cannabidiol
Abstract Chronic UV radiation causes oxidative stress and inflammation of skin and blood cells. Therefore, in this study, we assessed…
Efficacy and Safety of Cannabidiol Plus Standard Care vs Standard Care Alone for the Treatment of Emotional Exhaustion and Burnout Among Frontline Health Care Workers During the COVID-19 Pandemic
Abstract Question: Is cannabidiol (CBD) therapy capable of reducing emotional exhaustion and burnout symptoms among frontline health care professionals working…
Tamoxifen Sensitizes Acute Lymphoblastic Leukemia Cells to Cannabidiol by Targeting Cyclophilin-D and Altering Mitochondrial Ca2+ Homeostasis
Abstract Cytotoxic effects of cannabidiol (CBD) and tamoxifen (TAM) have been observed in several cancer types. We have recently shown…
Recalcitrance of Cannabis sativa to de novo regeneration; a multi-genotype replication study
Abstract Cannabis sativa is relatively recalcitrant to de novo regeneration, but several studies have reported shoot organogenesis or somatic embryogenesis…