Cancer Therapy Challenge: It Is Time to Look in the “St. Patrick’s Well” of the Nature
Abstract Cancer still remains a leading cause of death despite improvements in diagnosis, drug discovery and therapy approach. Therefore, there…
Free
Anti-Biofilm Activity of Cannabigerol against Streptococcus mutans
Abstract Streptococcus mutans is a common cariogenic bacterium in the oral cavity involved in plaque formation. Previous studies showed that…
Cannabis and Driving
Abstract As more states in the U.S legalize recreational and medicinal cannabis, rates of driving under the influence of this…
Pharmacological and Toxicological Effects of Phytocannabinoids and Recreational Synthetic Cannabinoids: Increasing Risk of Public Health
Abstract Synthetic Cannabinoids (CBs) are a novel class of psychoactive substances that have rapidly evolved around the world with the…
Cannabinoids, Medical Cannabis, and Colorectal Cancer Immunotherapy
Abstract Colorectal cancer is a major public health problem. Unfortunately, currently, no effective curative option exists for this type of…
Computational Approach Reveals Pronociceptive Potential of Cannabidiol in Osteoarthritis: Role of Transient Receptor Potential Channels
Abstract Systems pharmacology employs computational and mathematical methods to study the network of interactions a drug may have within complex…
Hepatic Cannabinoid Signaling in the Regulation of Alcohol-Associated Liver Disease
Abstract PURPOSE: The endocannabinoid system has emerged as a key regulatory signaling pathway in the pathophysiology of alcohol-associated liver disease…
Synthesis, characterization and stress-testing of a robust quillaja saponin stabilized oil-in-water phytocannabinoid nanoemulsion
Abstract Background: This study describes the design, optimization, and stress-testing of a novel phytocannabinoid nanoemulsion generated using high-pressure homogenization. \(\text…
Effect of Varying Levels of Hempseed Meal Supplementation on Humoral and Cell-Mediated Immune Responses of Goats
Abstract Simple Summary: Hempseed meal (HSM) is a byproduct of hemp oil production and is high in protein, fiber, and…
Recent Updates and Advances in Winiwarter-Buerger Disease (Thromboangiitis Obliterans): Biomolecular Mechanisms, Diagnostics and Clinical Consequences
Abstract Thromboangiitis obliterans (TAO) or Buerger’s disease is a segmental inflammatory, thrombotic occlusive peripheral vascular disease with unknown aetiology that…