Acute Extrapyramidal Side Effects from Smoked Haloperidol
Abstract Introduction: Haloperidol is a dopamine receptor antagonist used to treat patients with psychotic disorders. Especially at high doses, haloperidol…
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Activity-based anorexia animal model: a review of the main neurobiological findings
Abstract Background: The genesis of anorexia nervosa (AN), a severe eating disorder with a pervasive effect on many brain functions…
Cannabidiol Attenuates MK-801-Induced Cognitive Symptoms of Schizophrenia in the Passive Avoidance Test in Mice
Abstract Schizophrenia is a chronic mental disorder that disturbs feelings and behavior. The symptoms of schizophrenia fall into three categories:…
Cannabinoid Receptor 2 Alters Social Memory and Microglial Activity in an Age-Dependent Manner
Abstract Physiological brain aging is characterized by gradual, substantial changes in cognitive ability, accompanied by chronic activation of the neural…
A potential role for cannabichromene in modulating TRP channels during acute respiratory distress syndrome
Abstract Background: Acute respiratory distress syndrome (ARDS) is a life-threatening clinical syndrome whose potential to become one of the most…
The role of efflux transporters and metabolizing enzymes in brain and peripheral organs to explain drug‐resistant epilepsy
Abstract Drug‐resistant epilepsy has been explained by different mechanisms. The most accepted one involves overexpression of multidrug transporters proteins at…
Assessing the bioactivity of cannabis extracts in larval zebrafish
Abstract Background: Whole-plant cannabis extracts are consumed by the public for medical and non-medical (“recreational”) purposes but are poorly researched…
Exploring Impact of Marijuana (Cannabis) Abuse on Adults Using Machine Learning
Abstract Marijuana is the most common illicit substance globally. The rate of marijuana use is increasing in young adults in…
Adolescent administration of Δ9-THC decreases the expression and function of muscarinic-1 receptors in prelimbic prefrontal cortical neurons of adult male mice
Abstract Long-term cannabis use during adolescence has deleterious effects in brain that are largely ascribed to the activation of cannabinoid-1…
Cannabis sativa: From Therapeutic Uses to Micropropagation and Beyond
Abstract The development of a protocol for the large-scale production of Cannabis and its variants with little to no somaclonal…