Cannabidiol Induces Cell Death in Human Lung Cancer Cells and Cancer Stem Cells
Abstract Currently, there is no effective therapy against lung cancer due to the development of resistance. Resistance contributes to disease…
Free
Optimisation of Nitrogen, Phosphorus, and Potassium for Soilless Production of Cannabis sativa in the Flowering Stage Using Response Surface Analysis
Abstract Following legalisation, cannabis has quickly become an important horticultural crop in Canada and increasingly so in other parts of…
A 1D Model for Predicting Heat and Moisture Transfer through a Hemp-Concrete Wall Using the Finite-Element Method
Abstract Plant-based concrete is a construction material which, in addition to having a very low environmental impact, exhibits excellent hygrothermal…
Cannabidiol Does Not Cause Significant Changes to Working Memory Performance in the N-Back Task
Abstract Cannabis use can be traced back to several centuries before the Common Era, when it was used for industrial,…
Understanding the role of the CB1 toggle switch in interaction networks using molecular dynamics simulation
Abstract The cannabinoid receptor 1 (CB1) is a class A G-protein coupled receptor (GPCR) that can exert various effects on…
Nanoscale Sub-Compartmentalization of the Dendritic Spine Compartment
Abstract Compartmentalization of the membrane is essential for cells to perform highly specific tasks and spatially constrained biochemical functions in…
The Endocannabinoid System as a Pharmacological Target for New Cancer Therapies
Abstract Simple Summary: Cannabinoids have been shown to suppress tumour cell proliferation, tumour invasion, metastasis, angiogenesis, chemoresistance and epithelial-mesenchymal transition…
Microbiome of Field Grown Hemp Reveals Potential Microbial Interactions With Root and Rhizosphere Soil
Abstract Hemp (Cannabis sativa L.) is a crop bred and grown for the production of fiber, grain, and floral extracts…
The Influence of Chosen Plant Fillers in PHBV Composites on the Processing Conditions, Mechanical Properties and Quality of Molded Pieces
Abstract This work is inspired by the current European policies that aim to reduce plastic waste. This is especially true…
The terpenes camphene and alpha-bisabolol inhibit inflammatory and neuropathic pain via Cav3.2 T-type calcium channels
Abstract Supplementary Information: The online version contains supplementary material available at 10.1186/s13041-021-00876-6. Article type: Research Article Keywords: Pain, Terpenes, Bisabolol,…