Cannabidiolic acid in Hemp Seed Oil Table Spoon and Beyond
Abstract Cannabidiolic acid (CBDA) is the main precannabinoid in industrial hemp. It represents a common constituent of hemp seed oil,…
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Immunomodulatory Role of CB2 Receptors in Emotional and Cognitive Disorders
Abstract Emotional behavior, memory, and learning have been associated with alterations in the immune system in neuropsychiatric and neurodegenerative diseases.…
Cannabis Use and Neuroadaptation: A Call for Δ9-Tetrahydrocannabinol Challenge Studies
Abstract Currently, the assessment of the neurobehavioral consequences of repeated cannabis use is restricted to studies in which brain function…
Cannabinoid CB1 Receptor Involvement in the Actions of CBD on Anxiety and Coping Behaviors in Mice
Abstract The anxiolytic and antidepressant properties of cannabidiol (CBD) have been evaluated in several studies. However, the molecular mechanisms involved…
Prostanoid Signaling in Cancers: Expression and Regulation Patterns of Enzymes and Receptors
Abstract Simple Summary: Neoplastic processes are accompanied by the reprogramming of cell metabolism and alteration of the balance between endogenous…
Analyzing sentiments and themes on cannabis in Canada using 2018 to 2020 Twitter data
Abstract Introduction: The Canadian Cannabis Act came into effect on October 17, 2018, which allowed Canadian adults to consume cannabis…
Hempseed By-Product in Diets of Italian Simmental Cull Dairy Cows and Its Effects on Animal Performance and Meat Quality
Abstract Simple Summary: At the end of their productive career, dairy cows are culled without a fattening period and, therefore,…
Potential Pro-Inflammatory Effect of Vitamin E Analogs through Mitigation of Tetrahydrocannabinol (THC) Binding to the Cannabinoid 2 Receptor
Abstract Vitamin E acetate, which is used as a diluent of tetrahydrocannabinol (THC), has been reported as the primary causative…
Targeted Molecular Strategies for Genetic Neurodevelopmental Disorders: Emerging Lessons from Dravet Syndrome
Abstract Dravet syndrome is a severe developmental and epileptic encephalopathy mostly caused by heterozygous mutation of the SCN1A gene encoding…
Cannabidiol impairs neural tube closure in mouse whole embryo culture
Abstract Background: Cannabidiol (CBD) is a nonpsychoactive constituent of cannabis widely available as a dietary supplement. Previous reports that it…