Cannabinoids as anticancer drugs: current status of preclinical research
Abstract Drugs that target the endocannabinoid system are of interest as pharmacological options to combat cancer and to improve the…
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New AKT-dependent mechanisms of anti-COVID-19 action of high-CBD Cannabis sativa extracts
Abstract COVID-19 is caused by the SARS-CoV-2 virus, which enters target cells via interactions with ACE2 and TMPRSS2. Here, we…
Reward Sensitivity at Age 13 Predicts the Future Course of Psychopathology Symptoms
Abstract Background: There are numerous observations of reward sensitivity being associated with different psychiatric disorders. Nonetheless, most studies investigating this…
Non-Canonical Cannabinoid Receptors with Distinct Binding and Signaling Properties in Prostate and Other Cancer Cell Types Mediate Cell Death
Abstract Cannabinoids exert anti-cancer actions; however, the underlying cytotoxic mechanisms and the cannabinoid receptors (CBRs) involved remain unclear. In this…
Observational study of medical marijuana as a treatment for treatment‐resistant epilepsies
Abstract Objectives: Medical cannabis formulations with cannabidiol (CBD) and delta‐9‐tetrahydrocannabinol (THC) are widely used to treat epilepsy. We studied the…
Relationship between sense of coherence and health-related behaviours in adolescents and young adults: a systematic review
Abstract Background: The sense of coherence is developed through the learning process and contributes to the positioning of individuals in…
Anti-Microbial Activity of Phytocannabinoids and Endocannabinoids in the Light of Their Physiological and Pathophysiological Roles
Abstract Antibiotic resistance has become an increasing challenge in the treatment of various infectious diseases, especially those associated with biofilm…
Stability of the Fungal Pigment from Scytalidium cuboideum Carried in Food-Grade Natural Oils
Abstract Wood-staining fungal pigments have shown potential use as colorants for wood and textiles, with organic solvents as the pigment…
Medical Cannabis for Gilles de la Tourette Syndrome: An Open-Label Prospective Study
Abstract Objectives: Assessing the effectiveness and tolerability of medical cannabis (MC) treatment on Gilles de la Tourette syndrome (GTS) patients.…
ACPA Alleviates Bleomycin-Induced Pulmonary Fibrosis by Inhibiting TGF-β-Smad2/3 Signaling-Mediated Lung Fibroblast Activation
Abstract Pulmonary fibrosis is a group of life-threatening diseases with limited therapeutic options. The involvement of cannabinoid type 1 receptors…