Impact of the Aversive Effects of Drugs on Their Use and Abuse
Abstract Drug use and abuse are complex issues in that the basis of each may involve different determinants and consequences,…
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Cannabinoids Alleviate the LPS-Induced Cytokine Storm via Attenuating NLRP3 Inflammasome Signaling and TYK2-Mediated STAT3 Signaling Pathways In Vitro
Abstract Cannabinoids, mainly cannabidiol (CBD) and Δ9-tetrahydrocannabinol (THC), are the most studied group of compounds obtained from Cannabis sativa because…
Cannabidiol induces autophagy and improves neuronal health associated with SIRT1 mediated longevity
Abstract Supplementary Information: The online version contains supplementary material available at 10.1007/s11357-022-00559-7. Article type: Research Article Keywords: Cannabidiol, Aging, Autophagy,…
Prevalence and characteristics of cannabis-induced toxicoses in pets: Results from a survey of veterinarians in North America
Abstract Cannabis legalization in North America has coincided with an increase in reports of cannabis-induced toxicosis in pets, but the…
Pathogenic Mechanisms Underlying Cirrhotic Cardiomyopathy
Abstract Cardiac dysfunction associated with cirrhosis in the absence of preexisting heart disease is a condition known as cirrhotic cardiomyopathy…
Potential cannabidiol (CBD) repurposing as antibacterial and promising therapy of CBD plus polymyxin B (PB) against PB-resistant gram-negative bacilli
Abstract This study aimed to assess the ultrapure cannabidiol (CBD) antibacterial activity and to investigate the antibacterial activity of the…
Antiseizure Effects of Cannabidiol Leading to Increased Peroxisome Proliferator-Activated Receptor Gamma Levels in the Hippocampal CA3 Subfield of Epileptic Rats
Abstract We evaluated the effects of cannabidiol (CBD) on seizures and peroxisome proliferator-activated receptor gamma (PPARγ) levels in an animal…
An Open Retrospective Study of a Standardized Cannabidiol Based-Oil in Treatment-Resistant Epilepsy
Abstract Introduction: Cannabidiol (CBD) has antiseizure properties but no psychoactive effects. Randomized controlled trials of an oral, pharmaceutical formulation of…
Empirical Evaluation of Inflorescences’ Morphological Attributes for Yield Optimization of Medicinal Cannabis Cultivars
Abstract In recent decades with the reacknowledgment of the medicinal properties of Cannabis sativa L. (cannabis) plants, there is an…
Prenatal Opioid Exposure Impairs Endocannabinoid and Glutamate Transmission in the Dorsal Striatum
Abstract The opioid crisis has contributed to a growing population of children exposed to opioids during fetal development; however, many…