Tonic Endocannabinoid Levels Modulate Retinal Signaling
Abstract The endocannabinoid (eCB) system is critically involved in the modulation of synaptic transmission in the central nervous system, playing…
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Cannabinoids for behavioral symptoms in severe dementia: Safety and feasibility in a long-term pilot observational study in nineteen patients
Abstract Context: The management of behavioral symptoms and rigidity in patients with dementia constitutes a significant challenge. Short-term studies suggest…
Cannabinoid Therapeutic Effects in Inflammatory Bowel Diseases: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
Abstract (1) Introduction: Inflammatory Bowel Disease (IBD) patients may benefit from cannabinoid administration supplementary therapy; currently no consensus on its…
Cannabinoid therapeutics in orofacial pain management: a systematic review
Abstract The objective of this paper was to investigate the published evidence regarding effects of cannabinoids (natural and synthetic) on…
Medical cannabis for the treatment of comorbid symptoms in children with autism spectrum disorder: An interim analysis of biochemical safety
Abstract Background: Autistic Spectrum Disorder (ASD) is a common neurodevelopmental disorder and no effective treatment for the core symptoms is…
Genetic Evaluation of In Vitro Micropropagated and Regenerated Plants of Cannabis sativa L. Using SSR Molecular Markers
Abstract Simple sequence repeat (SSR) markers were used to evaluate the genetic stability of the acclimatized micropropagated and regenerated plants…
Too Dense or Not Too Dense: Higher Planting Density Reduces Cannabinoid Uniformity but Increases Yield/Area in Drug-Type Medical Cannabis
Abstract A major challenge for utilizing cannabis for modern medicine is the spatial variability of cannabinoids in the plant, which…
Cannabidiol modulates expression of type I IFN response genes and HIV infection in macrophages
Abstract Cannabis (Cannabis sativa) is a widely used drug in the United States and the frequency of cannabis use is…
Evaluation of Substance Use Disorder Readmission and Length of Hospital Stay in a Major Rehabilitation Center in the Gulf States: a Retrospective Cohort Study
Abstract Substance use disorders (SUDs) patients have longer lengths of hospital stay, and more unplanned readmissions than other hospitalized patients.…
Gram-Scale Preparation of Cannflavin A from Hemp (Cannabis sativa L.) and Its Inhibitory Effect on Tryptophan Catabolism Enzyme Kynurenine-3-Monooxygenase
Abstract Simple Summary: Kynurenine-3-monooxygenase (KMO) is an enzyme in the neurotoxic branch of the kynurenine pathway (KP) and is a…