Delta-8 Tetrahydrocannabinol Product Impurities
Abstract Due to increased concerns regarding unidentified impurities in delta-8 tetrahydrocannabinol (Δ-8 THC) consumer products, a study using Nuclear Magnetic…
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Genome-wide identification of key enzyme-encoding genes and the catalytic roles of two 2-oxoglutarate-dependent dioxygenase involved in flavonoid biosynthesis in Cannabis sativa L.
Abstract Background: Flavonoids are necessary for plant growth and resistance to adversity and stress. They are also an essential nutrient…
Optimal Treatment with Cannabis Extracts Formulations Is Gained via Knowledge of Their Terpene Content and via Enrichment with Specifically Selected Monoterpenes and Monoterpenoids
Abstract Differences between therapeutic effects of medical cannabis inflorescences and those of their extracts are generally attributed to the differences…
Cannabidiol in clinical and preclinical anxiety research. A systematic review into concentration–effect relations using the IB-de-risk tool
Abstract Background: Preclinical research suggests that cannabidiol (CBD) may have therapeutic potential in pathological anxiety. Dosing guidelines to inform future…
“Flower Power”: Controlled Inhalation of THC-Predominant Cannabis Flos Improves Health-Related Quality of Life and Symptoms of Chronic Pain and Anxiety in Eligible UK Patients
Abstract In November 2018, the UK’s Home Office established a legal route for eligible patients to be prescribed cannabis-based products…
Pilot clinical and pharmacokinetic study of Δ9-Tetrahydrocannabinol (THC)/Cannabidiol (CBD) nanoparticle oro-buccal spray in patients with advanced cancer experiencing uncontrolled pain
Abstract This pilot study aimed to assess the safety, tolerability, pharmacokinetics and exploratory analgesic effect of a novel water-soluble oro-buccal…
Effects of super-class cannabis terpenes beta-caryophyllene and alpha-pinene on zebrafish behavioural biomarkers
Abstract Terpenes possess a wide range of medicinal properties and are potential therapeutics for a variety of pathological conditions. This…
Genome-Wide Identification and Expression Analysis of Wall-Associated Kinase (WAK) Gene Family in Cannabis sativa L.
Abstract Wall-associated kinases (WAKs) are receptors that bind pectin or small pectic fragments in the cell wall and play roles…
Characterization and expression analysis of MATEs in Cannabis sativa L. reveals genes involving in cannabinoid synthesis
Abstract The medicinal plant Cannabis sativa L. (C. sativa) accumulates plant cytotoxic but medicinally important cannabinoids in glandular trichomes and…
Lip Bumper Therapy Does Not Influence the Sagittal Mandibular Incisor Position in a Retrospective CBCT Study
Abstract Lip bumper (LB) therapy is used as a treatment approach for mild to moderate crowding without extraction of teeth.…