A Clinical Framework for Assessing Cannabis-Related Impairment Risk
Abstract Clinicians play an important role in promoting safe and responsible medical cannabis use. One essential component to safe use…
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Multiomic Analysis Reveals Disruption of Cholesterol Homeostasis by Cannabidiol in Human Cell Lines
Abstract The nonpsychoactive cannabinoid, cannabidiol (CBD), is Food and Dug Administration approved for treatment of two drug-resistant epileptic disorders and…
Phytochemical Analysis of the Methanolic Extract and Essential Oil from Leaves of Industrial Hemp Futura 75 Cultivar: Isolation of a New Cannabinoid Derivative and Biological Profile Using Computational Approaches
Abstract Cannabis sativa L. is a plant belonging to the Cannabaceae family, cultivated for its psychoactive cannabinoid (Δ9-THC) concentration or…
Chronic Effects of Effective Oral Cannabidiol Delivery on 24-h Ambulatory Blood Pressure and Vascular Outcomes in Treated and Untreated Hypertension (HYPER-H21-4): Study Protocol for a Randomized, Placebo-Controlled, and Crossover Study
Abstract Accumulating data from both human and animal studies suggest that cannabidiol (CBD) may be associated with improved cardiovascular function,…
Differences in Inhibitory Control and Resting Brain Metabolism between Older Chronic Users of Tetrahydrocannabinol (THC) or Cannabidiol (CBD)—A Pilot Study
Abstract Δ9-Tetrahydrocannabinol is the main psychoactive component of cannabis and cannabidiol is purportedly responsible for many of the medicinal benefits.…
The Phytochemical Potential for Brain Disease Therapy and the Possible Nanodelivery Solutions for Brain Access
Abstract Plant-derived phytochemicals have gifted humans with vast therapeutic potentials. Yet, the unique features of the blood–brain barrier significantly limit…
Cannabinoid Effect and Safety in Spasticity Following Stroke: A Double-Blind Randomized Placebo-Controlled Study
Abstract Background: Nabiximols is a cannabis-based drug to treat spasticity-associated symptoms currently approved for patients with multiple sclerosis only. Cannabinoids…
A Temporary Immersion System to Improve Cannabis sativa Micropropagation
Abstract The aim of this study was to propagate axillary shoots of Cannabis sativa L. using liquid medium in temporary…
Epidemiology of Δ8THC-Related Carcinogenesis in USA: A Panel Regression and Causal Inferential Study
Abstract The use of Δ8THC is increasing at present across the USA in association with widespread cannabis legalization and the…
Cannabinoids in the Treatment of Cannabis Use Disorder: Systematic Review of Randomized Controlled Trials
Abstract Background: The prevalence of cannabis use and cannabis use disorders (CUD) has significantly increased over time. However, there are…