An Updated Review of the Genus Humulus: A Valuable Source of Bioactive Compounds for Health and Disease Prevention
Abstract The medicinal potential of hop (Humulus lupulus L.) is widely cited in ancient literature and is also allowed in…
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Phytoextraction Potential of Sunn Hemp, Sunflower, and Marigold for Carbaryl Contamination: Hydroponic Experiment
Abstract The phytoextraction ability and responses of sunn hemp, sunflower, and marigold plants were investigated toward carbaryl insecticide at 10…
Cannabidiol and Beta-Caryophyllene in Combination: A Therapeutic Functional Interaction
Abstract Cannabis contains over 500 distinct compounds, which include cannabinoids, terpenoids, and flavonoids. However, very few of these compounds have…
Safety and Tolerability of Oral Cannabinoids in People Living with HIV on Long-Term ART: A Randomized, Open-Label, Interventional Pilot Clinical Trial (CTNPT 028) †
Abstract Background: With anti-inflammatory properties, cannabinoids may be a potential strategy to reduce immune activation in people living with HIV…
An improved assembly of the “Cascade” hop (Humulus lupulus) genome uncovers signatures of molecular evolution and refines time of divergence estimates for the Cannabaceae family
Abstract We present a chromosome-level assembly of the Cascade hop (Humulus lupulus L. var. lupulus) genome. The hop genome is…
Phytocannabinoids Stimulate Rejuvenation and Prevent Cellular Senescence in Human Dermal Fibroblasts
Abstract In light of the increased popularity of phytocannabinoids (pCBs) and their appearance in beauty products without rigorous research on…
Secondary Terpenes in Cannabis sativa L.: Synthesis and Synergy
Abstract Cannabis is a complex biosynthetic plant, with a long history of medicinal use. While cannabinoids have received the majority…
Development and Validation of the LC–MS/MS Method for Determination of 130 Natural and Synthetic Cannabinoids in Cannabis Oil
Abstract Dietary supplements are widely available products used by millions of people around the world. Unfortunately, the procedure of adding…
GABAergic Neurotransmission in Human Tissues Is Modulated by Cannabidiol
Abstract Recently, the potential use of phytocannabinoids (pCBs) to treat different pathological conditions has attracted great attention in the scientific…
Discovery of a pyrano[2,3-b]pyridine derivative YX-2102 as a cannabinoid receptor 2 agonist for alleviating lung fibrosis
Abstract Background: Pharmacological modulation of cannabinoid 2 receptor (CB2R) is a promising therapeutic strategy for pulmonary fibrosis (PF). Thus, to…