Novel Insights into the Nature of Intraspecific Genome Size Diversity in Cannabis sativa L.
Abstract Cannabis sativa has been used for millennia in traditional medicine for ritual purposes and for the production of food…
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Socioeconomic, Ethnocultural, Substance- and Cannabinoid-Related Epidemiology of Down Syndrome USA 1986–2016: Combined Geotemporospatial and Causal Inference Investigation
Abstract Background: Down syndrome (DS) is the commonest of the congenital genetic defects whose incidence has been rising in recent…
Delta-8 Tetrahydrocannabinol Product Impurities
Abstract Due to increased concerns regarding unidentified impurities in delta-8 tetrahydrocannabinol (Δ-8 THC) consumer products, a study using Nuclear Magnetic…
Genome-wide identification of key enzyme-encoding genes and the catalytic roles of two 2-oxoglutarate-dependent dioxygenase involved in flavonoid biosynthesis in Cannabis sativa L.
Abstract Background: Flavonoids are necessary for plant growth and resistance to adversity and stress. They are also an essential nutrient…
Optimal Treatment with Cannabis Extracts Formulations Is Gained via Knowledge of Their Terpene Content and via Enrichment with Specifically Selected Monoterpenes and Monoterpenoids
Abstract Differences between therapeutic effects of medical cannabis inflorescences and those of their extracts are generally attributed to the differences…
“Flower Power”: Controlled Inhalation of THC-Predominant Cannabis Flos Improves Health-Related Quality of Life and Symptoms of Chronic Pain and Anxiety in Eligible UK Patients
Abstract In November 2018, the UK’s Home Office established a legal route for eligible patients to be prescribed cannabis-based products…
Pilot clinical and pharmacokinetic study of Δ9-Tetrahydrocannabinol (THC)/Cannabidiol (CBD) nanoparticle oro-buccal spray in patients with advanced cancer experiencing uncontrolled pain
Abstract This pilot study aimed to assess the safety, tolerability, pharmacokinetics and exploratory analgesic effect of a novel water-soluble oro-buccal…
Effects of super-class cannabis terpenes beta-caryophyllene and alpha-pinene on zebrafish behavioural biomarkers
Abstract Terpenes possess a wide range of medicinal properties and are potential therapeutics for a variety of pathological conditions. This…
Cannabidiol in clinical and preclinical anxiety research. A systematic review into concentration–effect relations using the IB-de-risk tool
Abstract Background: Preclinical research suggests that cannabidiol (CBD) may have therapeutic potential in pathological anxiety. Dosing guidelines to inform future…
Lip Bumper Therapy Does Not Influence the Sagittal Mandibular Incisor Position in a Retrospective CBCT Study
Abstract Lip bumper (LB) therapy is used as a treatment approach for mild to moderate crowding without extraction of teeth.…