Delta-8-THC association with psychosis: A case report with literature review
Abstract Background: Cannabis (Δ9-THC) is the most commonly consumed illicit drug. The Agricultural Improvement Act of 2018 removed hemp, a…
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Beyond CBD: Inhibitory effects of lesser studied phytocannabinoids on human voltage-gated sodium channels
Abstract Introduction: Cannabis contains cannabidiol (CBD), the main non-psychoactive phytocannabinoid, but also many other phytocannabinoids that have therapeutic potential in…
Efficacy and safety of topical 0.1% cannabidiol for managing recurrent aphthous ulcers: a randomized controlled trial
Abstract Background: Although topical steroids constitute the first-line therapy for recurrent aphthous ulcers (RAUs), their long-term use often leads to…
The Impact of COVID-19 Confinement on Substance Use and Mental Health in Portuguese Higher Education Students
Abstract The mental health of higher education students is a constant concern, and the pandemic situation caused by COVID-19 has…
Monitoring Perfusion Index in Patients Presenting to the Emergency Department Due to Drug Use
Abstract (1) Background: The perfusion index (PI) represents the ratio between pulsatile blood flow and non-pulsatile blood flow in the…
Combined ambient ionization mass spectrometric and chemometric approach for the differentiation of hemp and marijuana varieties of Cannabis sativa
Abstract Background: Hemp and marijuana are the two major varieties of Cannabis sativa. While both contain Δ9-tetrahydrocannabinol (THC), the primary…
Impacts of medical and non-medical cannabis on the health of older adults: Findings from a scoping review of the literature
Abstract Background: Cannabis legalization has enabled increased consumption in older adults. Age-related mental, physical, and physiological changes may lead to…
Genome-Wide Identification, Classification, and Expression Analyses of the CsDGAT Gene Family in Cannabis sativa L. and Their Response to Cold Treatment
Abstract Hempseed is a nutrient-rich natural resource, and high levels of hempseed oil accumulate within hemp seeds, consisting primarily of…
Prenatal Exposure to Δ9-Tetrahydrocannabinol Affects Hippocampus-Related Cognitive Functions in the Adolescent Rat Offspring: Focus on Specific Markers of Neuroplasticity
Abstract Previous evidence suggests that prenatal exposure to THC (pTHC) derails the neurodevelopmental trajectories towards a vulnerable phenotype for impaired…
Applied Clinical Tandem Mass Spectrometry-Based Quantification Methods for Lipid-Derived Biomarkers, Steroids and Cannabinoids: Fit-for-Purpose Validation Methods
Abstract The emergence of metabolomics and quantification approaches is revealing new biomarkers applied to drug discovery. In this context, tandem…