GABAergic Neurotransmission in Human Tissues Is Modulated by Cannabidiol
Abstract Recently, the potential use of phytocannabinoids (pCBs) to treat different pathological conditions has attracted great attention in the scientific…
Free
Discovery of a pyrano[2,3-b]pyridine derivative YX-2102 as a cannabinoid receptor 2 agonist for alleviating lung fibrosis
Abstract Background: Pharmacological modulation of cannabinoid 2 receptor (CB2R) is a promising therapeutic strategy for pulmonary fibrosis (PF). Thus, to…
Small molecules in the treatment of COVID-19
Abstract The outbreak of COVID-19 has become a global crisis, and brought severe disruptions to societies and economies. Until now,…
Hemp Shives as a Raw Material for the Production of Particleboards
Abstract Increased demand for wood affects its price and thus contributes to the growing interest in raw materials that can…
A Randomized, Triple-Blind, Comparator-Controlled Parallel Study Investigating the Pharmacokinetics of Cannabidiol and Tetrahydrocannabinol in a Novel Delivery System, Solutech, in Association with Cannabis Use History
Abstract Background: An oral route of administration for tetrahydrocannabinol (Δ9-THC) and cannabidiol (CBD) eliminates the harmful effects of smoking and…
In utero exposure to cannabidiol disrupts select early-life behaviors in a sex-specific manner
Abstract Cannabidiol (CBD), one of the main components of cannabis, is generally considered safe. CBD crosses the placenta and its…
Ultrasound-Assisted Extraction of Cannabinoids from Cannabis Sativa for Medicinal Purpose
Abstract Over the past 20 years, the interest in Cannabis oily extracts for medicinal use compounded in pharmacy has consistently…
Monitoring Cannabinoids and the Safety of the Trace Element Profile of Light Cannabis sativa L. from Different Varieties and Geographical Origin
Abstract Non-intoxicating Cannabis sativa L. (i.e., hemp) is increasingly used for industrial, cosmetic and food applications. Despite the fact that…
Cannabinoid Profiles in Medical Cannabis Users: Effects of Age, Gender, Symptoms, and Duration of Use
Abstract Introduction: Clinical trials remain the gold standard for evaluating efficacy, but there is increasing interest in using real-world evidence…
Increased White Matter Coherence Following Three and Six Months of Medical Cannabis Treatment
Abstract Background: Previous studies have demonstrated abnormal white matter (WM) microstructure in recreational cannabis consumers; however, the long-term impact of…