Candida Biofilm Eye Infection: Main Aspects and Advance in Novel Agents as Potential Source of Treatment
Abstract Fungi represent a very important cause of microbial eye infections, especially in tropical and developing countries, as they could…
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Update on neurobiological mechanisms of fear: illuminating the direction of mechanism exploration and treatment development of trauma and fear-related disorders
Abstract Fear refers to an adaptive response in the face of danger, and the formed fear memory acts as a…
Molecular pathway and structural mechanism of human oncochannel TRPV6 inhibition by the phytocannabinoid tetrahydrocannabivarin
Abstract The calcium-selective oncochannel TRPV6 is an important driver of cell proliferation in human cancers. Despite increasing interest of pharmacological…
Associations of U.S. state-level COVID-19 policies intensity with cannabis sharing behaviors in 2020
Abstract Background: Cannabis use before the COVID-19 pandemic for many involved sharing prepared cannabis for inhalation, practices that were less…
Evaluation of Field Sobriety Tests for Identifying Drivers Under the Influence of Cannabis
Abstract This randomized clinical trial investigates the accuracy of field sobriety tests administered by law enforcement officers to assess functional…
Could cannabinoids provide a new hope for ovarian cancer patients?
Abstract It is known that gynecological cancers remain a worldwide problem and as shown by the statistics, there is a…
Socio-Demographics of Initial Substance Use Exposure and Its Relation to Progression: A Cross-Sectional Study in Saudi Arabia
Abstract Introduction: Empirical evidence on substance use in Saudi Arabia is lacking. This quantitative study is aimed at describing the…
Phytocannabinoid-rich galenic preparations for topical administration: extraction and stability testing
Abstract Although medical cannabis was legalized in Czechia in 2013 and its use in topical treatments of skin disorders is…
Trends in Prescription Chronic Pain Medication Use before and during the First Wave of the COVID-19 Pandemic in Québec, Canada: An Interrupted Time Series Analysis
Abstract Background: In Canada, a state of health emergency was declared in May 2020 as a result of the COVID-19…
Polydrug Use among Students in a Public University in a Lower Middle-Income Country
Abstract Recreational drug use among students in tertiary institutions remains a public health concern. Despite documentation of drug use in…