Molecular and Cellular Mechanisms of Action of Cannabidiol
Abstract Cannabidiol (CBD) is the primary non-psychoactive chemical from Cannabis Sativa, a plant used for centuries for both recreational and…
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Is Cannabis Effective in the Treatment of Chronic Back Pain?
Abstract Cannabis is commonly recognized as a recreational substance. It has been explored for its potential therapeutic applications in addressing…
Simultaneous Assessment of Serum Levels and Pharmacologic Effects of Cannabinoids on Endocannabinoids and N-Acylethanolamines by Liquid Chromatography–Tandem Mass Spectrometry
Abstract Introduction: The primary compounds of Cannabis sativa, delta-9-tetrahydrocannabinol (Δ9-THC) and cannabidiol (CBD), inflict a direct influence on the endocannabinoid…
Pharmacokinetic modelling of orally administered cannabidiol and implications for medication control in horses
Abstract Cannabidiol (CBD) products gain increasing popularity amongst animal owners and veterinarians as an alternative remedy for treatment of stress,…
Etoricoxib-Cannabidiol Combo: Potential Role in Glioblastoma Treatment and Development of PLGA-Based Nanoparticles
Abstract Background: Glioblastoma (GBM) is the most frequently occurring primary malignant central nervous system tumor, with a poor prognosis and…
A systematic review of economic evaluations for opioid misuse, cannabis and illicit drug use prevention
Abstract Background: Substance use disorders negatively affect global disease burden. Effective preventive interventions are available, but whether they provide value…
Prevalence and factors associated with suicidal ideation, cannabis, and alcohol use during the COVID-19 pandemic in Saskatchewan: findings from a joint-effect modeling
Abstract Background: Generally, pandemics such as COVID-19 take an enormous toll on people’s lives. As the pandemic now turns to…
Disparities in cannabis use and documentation in electronic health records among children and young adults
Abstract The legalizations of medical and recreational cannabis have generated a great deal of interest in studying the health impacts…
Role of TRP Channels in Liver-Related Diseases
Abstract The liver plays a crucial role in preserving the homeostasis of an entire organism by metabolizing both endogenous and…
Chemsex and its repercussions on the health of men who have sex with men (MSM): a global health perspective
Abstract Objectives: to discuss the repercussions of chemsex on the health of men who have sex with men (MSM), contextualizing…