CBGA ameliorates inflammation and fibrosis in nephropathy
Abstract Cannabidiol (CBD) is thought to have multiple biological effects, including the ability to attenuate inflammatory processes. Cannabigerols (CBGA and…
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Unveiling behavioral and molecular neuroadaptations related to the antidepressant action of cannabidiol in the unpredictable chronic mild stress model
Abstract Introduction: This study aims to further characterize cannabidiol’s pharmacological and molecular profile as an antidepressant. Methods: Effects of cannabidiol…
Subtypes in addiction and their neurobehavioral profiles across three functional domains
Abstract Rates of return to use in addiction treatment remain high. We argue that the development of improved treatment options…
Repositioning Cannabinoids and Terpenes as Novel EGFR-TKIs Candidates for Targeted Therapy Against Cancer: A virtual screening model using CADD and biophysical simulations
Abstract This study examines the potential of Cannabis sativa L. plants to be repurposed as therapeutic agents for cancer treatment…
Cannabis Pharmacogenomics: A Path to Personalized Medicine
Abstract Cannabis and related compounds have created significant research interest as a promising therapy in many disorders. However, the individual…
Development of an Effective Acne Treatment Based on CBD and Herbal Extracts: Preliminary In Vitro, Ex Vivo, and Clinical Evaluation
Abstract Acne vulgaris, the most common form of acne, is characterized by a mixed eruption of inflammatory and noninflammatory skin…
The impact of 12 modifiable lifestyle behaviours on depressive and anxiety symptoms in middle adolescence: prospective analyses of the Canadian longitudinal COMPASS study
Abstract Background: Unhealthy lifestyle behaviours are becoming increasingly common and might contribute to the growing burden of mental disorders in…
Investigation of the Effect of the Auxin Antagonist PEO-IAA on Cannabinoid Gene Expression and Content in Cannabis sativa L. Plants under In Vitro Conditions
Abstract The in vitro shoot propagation of Cannabis sativa L. is an emerging research area for large-scale plant material production.…
Patterns of tobacco product use and substance misuse among adolescents in the United States
Abstract The use of e-cigarettes in combination with other tobacco products among youth is not uncommon. Sole e-cigarette, dual and…
Novel Synthesis of C-Methylated Phytocannabinoids Bearing Anti-inflammatory Properties
Abstract There is growing interest in non-psychoactive phytocannabinoids, namely cannabidiol (CBD), cannabigerol (CBG), and cannabichromene, as potential leads for novel…